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2026 (1)
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The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia (1)
Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia (1)

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Cryo-EM structure of endogenous Plasmodium falciparum Pfs230 and Pfs48/45 fertilization complex

Plasmodium falciparum Pfs230 and Pfs48/45 are the leading candidates for malaria transmission-blocking vaccines. However, it remains unknown how the two interact and if additional domains in Pfs230 are potential vaccine candidates. Here we report a 3.36 Å resolution cryo-electron microscopy structur...

ORGANISM(S): Plasmodium falciparum (isolate 3D7)

2025-08-08 | PXD060667 | Pride

Nanobodies peptide/glycopeptide identification

Confirmation of Nanobody sequences and identification of Nanobody glycopeptide glycoforms.

ORGANISM(S): Lama glama

2021-09-09 | PXD023483 | Pride

Ms-ms Glycopeptides Nanobodies

Pfs230 and Pfs48/45 complex SDA XL-MS

Asexual P. falciparum parasite cultures were maintained, gametocytes harvested and pellets lysed prior to chromatography procedures including size exclusion. Chemical cross-linking MS (XL-MS) analysis using SDA and UV exposure was performed followed by SDS-PAGE, gel bands excised and subjected to tr...

ORGANISM(S): Plasmodium (plasmodium)

2026-01-27 | PXD060341 | JPOST Repository

WEHI991 drug target identification by DIA Solvent PISA

Here we demonstrate PfSTART1 engagement by WEHI991 in the P. falciparum proteome using organic solvent-based Proteome Integral Solubility Alteration (Solvent PISA) assay coupled with Data Independent Acquisition Mass Spectrometry (DIA-MS).

ORGANISM(S): Plasmodium (plasmodium)

2024-05-01 | PXD048262 | JPOST Repository

Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic.

Not available

S-EPMC10364875 | biostudies-literature

A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.