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The pathogenesis of viral myocarditis is a multifactorial process involving host genetics, viral genetics and the environment in which they interact. Here, we used a model of infection with Coxsackievirus B3 to characterize the contribution of host genetics to viral myocarditis. We determined heart ...
ORGANISM(S): Mus musculus 
Description: These date form the basis for supplementary table 2 and supplementary figure 6 of the manuscript "Modelling glycan processing reveals Golgi-enzyme homeostasis upon trafficking defects and cellular differentiation" by P Fisher, H Spencer, J Thomas-Oates, AJ Wood, D Ungar in Cell Reports
ORGANISM(S): Homo sapiens (Human) 
2019-11-11 | PXD013211 | Pride
Seasonal influenza outbreaks and recurrent influenza pandemics present major challenges to public health. By studying immunological responses to influenza in different host species, it may be possible to discover common mechanisms of susceptibility in response to various influenza strains. This coul...
ORGANISM(S): Mus musculus 
Paper title: The antimicrobial potential of Streptomyces from insect microbiomes. Author list: Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns KJ, Book AJ, Cagnazzo J, Carlos C, Flanigan W, Grubbs KJ, Horn HA, Hoffmann FM, Klassen JL, Knack JJ, Lewin GR, McDonald BR, Muller L, Melo ...
ORGANISM(S): Pseudonocardia Kitasatospora Streptomyces Gordonia <actinomycete> 
2019-12-18 | MSV000084723 | MassIVE
To compare four- and seven-day-old Arabidopsis thaliana plasmodesmata proteome, the identification and the relative amount of proteins in plasmodesmata, cell wall and total cell extracts were performed using fractions purified from four- and seven-day-old liquid culture cells of A. thaliana. The rel...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-07-05 | PXD006806 | Pride
To establish the plasmodesmata core proteome, the identification and the relative amount of proteins in different cellular fractions, namely, the plasmodesmata, plasma membrane, total cell extract, microsomal and cell wall fractions, were determined using label-free quantification method. Four to si...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-07-05 | PXD006800 | Pride
Sirtuin 6 (SIRT6) is a deacylase and mono-ADP ribosyl transferase (mADPr) enzyme involved in multiple cellular pathways implicated in the regulation of aging and metabolism. Targeted sequencing identified a SIRT6 allele containing two linked substitutions (N308K/A313S) as enriched in Ashkenazi Jewis...
ORGANISM(S): Homo sapiens (Human) 
2022-10-21 | PXD035689 | Pride
Paper title: The antimicrobial potential of Streptomyces from insect microbiomes. Author list: Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns KJ, Book AJ, Cagnazzo J, Carlos C, Flanigan W, Grubbs KJ, Horn HA, Hoffmann FM, Klassen JL, Knack JJ, Lewin GR, McDonald BR, Muller L, Melo ...
ORGANISM(S): Kitasatospora (ncbitaxon:2063) Gordonia <actinomycete> (ncbitaxon:2053) Pseudonocardia (ncbitaxon:1847) Streptomyces (ncbitaxon:1883) 
2019-12-18 | MSV000084723 | GNPS
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
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