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Chlamydia trachomatis is an obligate intracellular bacterial pathogen and a leading cause of sexually transmitted infections worldwide. During its biphasic developmental cycle, infectious, non-replicative elementary bodies alternate with replicative reticulate bodies within a membrane-bound intra...

2026-08-10 | MTBLS15303 | MetaboLights
Trifunctional PIP3 is a chemically modified derivate of PIP3 that includes 3 functionalized groups allowing spacial an temporal manipulation of its release and function. A caged group allows for timed release of the coumpound, a cross-linking group induces covalent binding to binders, while a clicka...
ORGANISM(S): Homo sapiens (Human) 
2025-02-19 | PXD025903 | Pride
In this study, we employed chemically synthesized trifunctional lipid probes to identify putative protein partners that interact with lipids in HeLa cells. These probes incorporate three distinct chemical functionalities. First, a coumarin-based “caging” moiety is added to the lipid head group, whic...
ORGANISM(S): Homo sapiens (Human) 
2025-01-21 | PXD059960 | Pride
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