Sort   by:  
 Page size 
ProteomicsTryptic shaving of Staphylococcus aureus
Surface proteins of Gram-positive bacteria are critical for adherence to host tissues, evasion of the immune system, and interaction with the environment. They can be utilized as biomarkers in diagnostics, for vaccine development, and as therapeutic targets due to their accessibility and role in pat...
ORGANISM(S): Bacteria Staphylococcus aureus 
2025-09-15 | PXD061994 | Pride
Diagnostic peptides Surface proteins Staphylococcus aureus Tryptic shaving Proteomics 
ProteomicsStreptococcus pneumoniae biomarker identification by surface shaving and bottom-up mass spectrometry-based proteomics
In this study, genomics- and proteomics-based approaches were used for the identification of Streptococcus pneumoniae potential biomarkers for diagnostics and prospective targets for treatment. Through a Pan-genome analyses 11 strains from the CCUG demonstrating genetic variability within the speci...
ORGANISM(S): Streptococcus pneumoniae Bacteria 
2025-12-15 | PXD063486 | Pride
Proteomics Surface-shaving Bottom-up mass spectrometry Lpi Biomarkers Streptococcus pneumoniae 
ProteomicsProteomic study of Staphylococcus haemolyticus after the host-microbe co-colonisation
In this study, the adhesive and biofilm forming properties of ten clinical and ten commensal S. haemolyticus isolates were examined using standard adhesion and biofilm assays, in addition we selected one clinical S. haemolyticus isolate for bacterial surface shaving. The surface shaving approach was...
ORGANISM(S): Staphylococcus haemolyticus 
2020-05-26 | PXD014450 | Pride
Tandem mass tag Surface shaving Tmt Staphylococcus haemolyticus Q exactive hf 
ProteomicsTryptic striptease of Staphylococcus aureus unveils the cell surface localization of immunodominant epitopes
The opportunistic pathogen Staphylococcus aureus has become a major threat for human health and well-being by developing resistance to antibiotics, and by its fast evolution into new lineages that rapidly spread within the healthy human population. This calls for the development of active or passive...
ORGANISM(S): Staphylococcus aureus (strain Newman) Staphylococcus aureus (strain USA300) 
2020-06-18 | PXD000156 | Pride
Cellwall Surfacome Exoproteome Staphylococcus aureus Virulence factor 
ProteomicsSurface-shaving of Staphylococcus aureus strains using Lipid-based Protein Immobilization (LPI) and quantitative proteomic analysis reveal differences in protein expression levels of the surfaceome
Staphylococcus aureus is a pathogen which can cause a wide range of infections. To find new targets for diagnostics and treatment as well as understanding host-pathogen interactions, many studies have focused on the bacterial surface proteins. In the study presented here, bacterial cell surface-shav...
ORGANISM(S): Staphylococcus aureus 
2024-10-17 | PXD025436 | Pride
Proteomics Relative quantification Mass spectrometry Virulence factors Staphylococcus aureus Surfaceome Tandem mass tags 
ProteomicsGrowth condition-dependent cell surface proteome analysis of Enterococcus faecium
Using a proteolytic shaving approach we identified differentially expressed surface exposed proteins of E. faecium cells after growth in different conditions.
ORGANISM(S): Enterococcus Faecium E1162 (ncbitaxon:535206) 
2015-07-07 | MSV000079184 | MassIVE
ProteomicsProteomic analysis of intact flagella of procyclic Trypanosoma brucei cells identifies novel flagellar proteins with unique sub-localisation and dynamics
Identification of intact flagella of procyclic Trypanosoma brucei cells by LC-MS/MS after a trypsin shaving
ORGANISM(S): Trypanosoma brucei 
2018-12-17 | PXD000051 | Pride
Trypanosoma brucei Flagellar proteins Lc-ms/ms 
ProteomicsMycobacterium tuberculosis surface proteomics
Surface shaving Mtb using two concentrations of trypsin: 0.4 ug/mL and 0.05 ug/mL. Both bacteria and supernatant without the bacteria were subject to trypsinization, to allow for a ratio between samples to identify candidate surface proteins.
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2024-12-11 | PXD052936 | Pride
Surface Proteomics Mtb 
UnknownMass Spectrometry-Based Analysis of Surface Proteins in <i>Staphylococcus aureus</i> Clinical Strains: Identification of Promising k-mer Targets for Diagnostics.
Not available
S-EPMC12418492 | biostudies-literature
ProteomicsProteomic analysis of human SKBR3/HER2+ breast cancer cell-surface proteins by using tryptic shaving
The plasma membrane proteome resides at the interface between the extra- and intra-cellular environment and through its various roles in signal transduction, immune recognition, nutrient transport, and cell-cell and cell-matrix interactions plays a critical role in determining the fate of a cell. Th...
ORGANISM(S): Homo sapiens (Human) 
2022-07-11 | PXD028978 | Pride
Cancer Skbr3 cells Cell-surface proteins 
Sort   by:  
 Page size