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TranscriptomicsGene expression data from human NSCLC U1810 residual clones 9 days after a one-hour pulse treatment with cisplatin
Background: The platinum compounds cisplatin and carboplatin are the mainstay of chemotherapy for lung cancer; however, treatment failure remains a critical issue since about 60% of all non-small cell lung cancer (NSCLC) patients display intrinsic platinum resistance. Methods: We analyzed global gen...
ORGANISM(S): Homo sapiens 
2014-04-04 | E-GEOD-48244 | biostudies-arrayexpress
ProteomicsProteomics of U1810 cells upon treatment with microRNAs with an AAGUGC seed motif.
microRNA dysregulation is a common feature of cancer cells, but the complex roles of microRNAs in cancer are not fully elucidated. Here we used functional genomics to identify oncogenic microRNAs in non-small cell lung cancer and to evaluate their impact on response to EGFR targeting therapy. Our da...
ORGANISM(S): Homo sapiens (Human) 
2016-06-28 | PXD004163 | Pride
Human Mirna Lc-ms Microrna U1810 Hirief 
GenomicsGRO-seq analysis U1810 cells after 8h Rapamycin treatment and DMSO control
GRO-seq analysis U1810 cells after 8h Rapamycin treatment and DMSO control
PRJEB19325 | ENA
TranscriptomicsGRO-seq analysis U1810 cells after 8h Rapamycin treatment and DMSO control
Investigating transcriptional changes after autophagy induction by rapamycin to compare changes in autophagy-related genes to changes in histone modifications.
ORGANISM(S): Homo sapiens 
2017-02-03 | E-MTAB-5490 | biostudies-arrayexpress
GenomicsHomo sapiens
Gene expression data from human NSCLC U1810 residual clones 9 days after a one-hour pulse treatment with cisplatin
PRJNA209344 | ENA
UnknownSuppressed translation and ULK1 degradation as potential mechanisms of autophagy limitation under prolonged starvation.
Not available
S-EPMC5103336 | biostudies-literature
TranscriptomicsGene expression data from human NSCLC U1810 residual clones 9 days after a one-hour pulse treatment with cisplatin
Background: The platinum compounds cisplatin and carboplatin are the mainstay of chemotherapy for lung cancer; however, treatment failure remains a critical issue since about 60% of all non-small cell lung cancer (NSCLC) patients display intrinsic platinum resistance. Methods: We analyzed global gen...
ORGANISM(S): Homo sapiens 
2014-04-04 | GSE48244 | GEO
UnknownSuppressed translation as a mechanism of initiation of CASP8 (caspase 8)-dependent apoptosis in autophagy-deficient NSCLC cells under nutrient limitation.
Not available
S-EPMC5902222 | biostudies-literature
UnknownEffects of redox modulation by inhibition of thioredoxin reductase on radiosensitivity and gene expression.
Not available
S-EPMC3823227 | biostudies-literature
Proteomics,MultiomicsProteomics of U1810 cells upon treatment with microRNAs with an AAGUGC seed motif.
microRNA dysregulation is a common feature of cancer cells, but the complex roles of microRNAs in cancer are not fully elucidated. Here we used functional genomics to identify oncogenic microRNAs in non-small cell lung cancer and to evaluate their impact on response to EGFR targeting therapy. Our da...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080829 | MassIVE
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