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UnknownBenzimidazoles Downregulate Mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells.
Not available
S-EPMC6600429 | biostudies-literature
UnknownMetabolic stress regulates ERK activity by controlling KSR-RAF heterodimerization.
Not available
S-EPMC5797961 | biostudies-literature
UnknownCDK9 activity is critical for maintaining MDM4 overexpression in tumor cells.
Not available
S-EPMC7494941 | biostudies-literature
UnknownThe plasmamembrane calmodulin-dependent calcium pump: a major regulator of nitric oxide synthase I.
Not available
S-EPMC2198825 | biostudies-literature
UnknownUbiquitin-specific peptidase 48 regulates Mdm2 protein levels independent of its deubiquitinase activity.
Not available
S-EPMC5324091 | biostudies-literature
ProteomicsLC-MS analysis of human melanoma cell line response to eIF4F inhibition and MEK inhibition
The project aimed to identify changes at the protein level in human melanoma cells treated with the eIF4F inhibitor rocaglamide A, the MEK inhibitor PD184352 (CI-1040), and their combination. A375 and MelJuso human melanoma cell lines were cultured in RPMI 1640 medium supplemented with 10% fetal bov...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD073251 | Pride
Eif4a Human Inhibitor Rocaglamide a Small-molecule Ci-1040 Melanoma Pd184352 Cell line Meljuso A375 Lc-ms Eif4f Mek 
UnknownA Single Conserved Amino Acid Residue as a Critical Context-Specific Determinant of the Differential Ability of Mdm2 and MdmX RING Domains to Dimerize.
Not available
S-EPMC6465955 | biostudies-literature
UnknownRNA-seq Characterization of Melanoma Phenotype Switch in 3D Collagen after p38 MAPK Inhibitor Treatment.
Not available
S-EPMC8002814 | biostudies-literature
UnknownMammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs.
Not available
S-EPMC3884668 | biostudies-literature
UnknownA small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein.
Not available
S-EPMC5626491 | biostudies-literature
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