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ProteomicsSpermidine is essential for fasting-mediated autophagy and longevity
Caloric restriction and intermittent fasting prolong the lifespan and healthspan of model organisms and improve human health 1. The natural polyamine spermidine has been linked to autophagy regulation, geroprotection and reduced incidence of cardiovascular and neurodegenerative diseases across speci...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-04-30 | PXD035909 | Pride
Autophagy Nanolc-ms/ms Spermidin Fasting Yeast Human Lifespan Eif5a hypusination Mouse C.elegans 
UnknownBehavioural individuality determines infection risk in clonal ant colonies.
Not available
S-EPMC10460416 | biostudies-literature
UnknownIdentification of Catecholamine and Drug Target α2A-Adrenoceptor in Human Testis and Human Testicular Peritubular Cells.
Not available
S-EPMC11313226 | biostudies-literature
ProteomicsIdentification of a catecholamine- and drug-target, the α2A-adrenoceptor, in human testis and human testicular perit-ubular cells
Abstract: Clonidine has been used in clinical medicine, e.g. to treat high blood pressure, and its use has been linked to impairments of male fertility, but the underlying reasons are not known. Clonidine is an agonist at the α2A-adrenoceptor (ADRA2A) which is expressed by cells of the testis, hence...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD052220 | Pride
Human male fertility  human testis Testis Inflammation Contraction Peritubular cell Cytokines Alpha-adrenoreceptor Clonidine Sperm transport 
UnknownTherapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
Not available
S-EPMC4962737 | biostudies-literature
UnknownApplication of a comprehensive approach to pathogen screening in a stowaway rat on an airplane
Not available
S-EPMC12398574 | biostudies-literature
ProteomicsCharacterization of various cell lines from different ampullary cancer subtypes and cancer associated fibroblast-mediated responses
Introduction: Ampullary cancer is a relatively rare entity and usually treated by pancreatoduodenectomy followed by adjuvant therapy. The intestinal subtype is associated with markedly improved prognosis after resection. Only few cell lines are available for in vitro studies of ampullary cancer and ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080802 | MassIVE
TranscriptomicsThe evolution of lncRNA repertoires and expression patterns in tetrapods
Only a minuscule fraction of long non-coding RNAs (lncRNAs) are well characterized. The evolutionary history of lncRNAs can provide insights into their functionality, but comparative analyses have been precluded by our ignorance of lncRNAs in non-model organisms. Here, we use RNA sequencing to ident...
ORGANISM(S): Ornithorhynchus anatinus 
2014-01-19 | E-GEOD-43520 | biostudies-arrayexpress
UnknownLethal Borna disease virus 1 infections of humans and animals - in-depth molecular epidemiology and phylogeography.
Not available
S-EPMC11387626 | biostudies-literature
TranscriptomicsRNA-seq of 6 tissues from Homo sapiens to investigate the evolution of gene expression levels in mammalian organs
This experiment contains the subset of data corresponding to human RNA-Seq data from experiment E-GEOD-30352 (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30352/), which goal is to understand the dynamics of mammalian transcriptome evolution. To study mammalian transcriptome evolution at hig...
ORGANISM(S): Homo sapiens 
2011-10-12 | E-MTAB-3716 | biostudies-arrayexpress
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