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UnknownFormation of disulfide bridges drives oligomerization, membrane pore formation, and translocation of fibroblast growth factor 2 to cell surfaces.
Not available
S-EPMC4423683 | biostudies-literature
ProteomicsInterferon-induced degradation of the hepatitis B virus persistence form, cccDNA, depends on ISG20
Hepatitis B virus (HBV) persists by depositing a covalently closed circular DNA (cccDNA) in the nucleus of infected cells that cannot be targeted by available antivirals. Cytokine treatments can diminish HBV cccDNA via APOBEC3-mediated deamination. Here we show that overexpression of APOBEC3A alone,...
ORGANISM(S): Homo sapiens (Human) 
2021-04-22 | PXD019285 | Pride
Isg20 Apobec3a Hbv Interferon-gamma Cccdna Chronic hepatitis b Interferon-alpha 
UnknownClinical characteristics and comparison of longitudinal qPCR results from different specimen types in a cohort of ambulatory and hospitalized patients infected with monkeypox virus.
Not available
S-EPMC9528238 | biostudies-literature
UnknownInterferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20
Not available
S-SCDT-EMBOR-2019-49568-T | biostudies-other
TranscriptomicsDefective removal of ribonucleotides from DNA promotes systemic autoimmunity
Constitutive low level DNA damage in RNASEH2 deficiency is linked to innate immune activation. Hierarchical clustering of over 16000 transcripts revealed remarkably similar profiles in patients with lupus erythematosus and patients with AGS with up-regulation of genes involved in DNA damage signalin...
ORGANISM(S): Homo sapiens 
2014-12-15 | E-GEOD-63755 | biostudies-arrayexpress
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