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Alpha-synuclein (aSyn) is a central player in the pathogenesis of synucleinopathies due to its accumulation in typical protein aggregates in the brain. However, it is still unclear how it contributes to neurodegeneration. Type-2 diabetes mellitus is a risk factor for Parkinson’s disease (PD) ...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD032832 | Pride
In order to identify new regulators of the phosphate (Pi) starvation signaling pathway in plants, we analyzed variation in the abundance of nuclear-enriched nuclear proteins isolated from Arabidopsis roots that depends on Pi supply. We used 2-D Fluorescence Difference Gel Electrophoresis and MALDI-T...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2020-01-22 | PXD000305 | Pride
A collection of stable Drosophila S2 cell lines was established, each one expressing a (His)-PC SNAP tagged version of each of the six Elongator subunits. From these stable lines, the endogenous Elongator complex can be recovered by pulling on the exogenous subunit via the PC tag. This allowed us to...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-09-15 | PXD036556 | Pride
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