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ProteomicsEngineering of TurboID-Wingless for the identification of Wingless interactors through in vivo proximity labelling
Wnt signalling coordinates growth and cell fate decisions during development and mis-regulation of Wnt signalling in adults is associated with a range of conditions, including cancer and neurogenerative diseases. Therefore, means of modulating Wnt proteins and/or cofactors could have significant the...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2026-08-13 | PXD051416 | Pride
Wnt Proximity labelling Turboid 
ProteomicsRibosomal protein deficiency generates proteotoxic stress that is alleviated by TOR inhibition
Ribosomes are multi-component molecular machines that synthesize all the proteins of living cells. Understandably, most genes encoding the protein components of ribosomes are essential. Reduction in gene dosage is often viable but deleterious and associated with human syndromes, collectively known a...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-01-14 | PXD023021 | Pride
Eif2 Protein translation Diamond blackfan anemia Ribosomes Autophagy Rps23 Ribosomopathies Protein aggregates Tor Proteotoxic stress Apoptosis P62 Rps26 
UnknownPhenotypic discordance between primary and metastatic breast cancer in the large-scale real-life multicenter French ESME cohort.
Not available
S-EPMC8052407 | biostudies-literature
UnknownProcalcitonin algorithm to guide initial antibiotic therapy in acute exacerbations of COPD admitted to the ICU: a randomized multicenter study.
Not available
S-EPMC5924665 | biostudies-literature
UnknownNationwide incidence of sarcomas and connective tissue tumors of intermediate malignancy over four years using an expert pathology review network.
Not available
S-EPMC7906477 | biostudies-literature
UnknownEffects of mean arterial pressure on arousal in sedated ventilated patients with septic shock: a SEPSISPAM post hoc exploratory study.
Not available
S-EPMC6509319 | biostudies-literature
UnknownWhite blood count, D-dimers, and ferritin levels as predictive factors of pulmonary embolism suspected upon admission in noncritically ill COVID-19 patients: The French multicenter CLOTVID retrospective study.
Not available
S-EPMC8239942 | biostudies-literature
UnknownTarget trial emulation to replicate randomised clinical trials using registry data in multiple sclerosis.
Not available
S-EPMC12911643 | biostudies-literature
UnknownNeurologic manifestations associated with COVID-19: a multicentre registry.
Not available
S-EPMC7661948 | biostudies-literature
UnknownLack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection.
Not available
S-EPMC11215417 | biostudies-literature
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