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MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
ProteomicsRats, Brain, LC-MSMS - iTRAQ-Based Proteomics Analysis Reveals the Effect of Rhubarb in Rats with Ischemic Stroke
In our study, we apply isobaric tag for relative and absolute quantitation (iTRAQ) followed by multidimensional liquid chromatography and tandem MS analysis(LC-MS-MS). The iTRAQ labeling were performed according to the manufacturer's protocol (Applied Biosystems).8 groups of samples were labeled and...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-24 | PXD006437 | Pride
Lc-msms Brain Rats 
MetabolomicsSymbiotic bacteria-derived organic acids protect Delia antiqua larvae from entomopathogenic fungal infection

The protection of associated microbiota for their animal hosts against pathogen infection has been studied widely over the last 100 years. However, how those microbes protect the animal host is limitedly investigated. In former studies, body surface microbes of one insect, Delia antiqua,...

2020-11-12 | MTBLS2074 | MetaboLights
ProteomicsSerratia bacteria Su_YN1 OMV LC-MSMS
This project aims to analyse the proteins of outer membrane vesicles (OMVs) released by a Serratia bacteria strain Su_YN1, which is isolated from field-caught mosquito gut. Su_YN1 produces massive OMVs under host serum induction. The data contain LC-MSMS results of the OMVs released without serum in...
ORGANISM(S): Serratia ureilytica 
2023-08-02 | PXD042831 | Pride
Serratia omv mosquito lipase plasmodium 
ProteomicsDSSO,Xlink,LC-MSMS - DSSO as linker, study of protein-protein interaction by LC-MSMS
DSSO as linker, study of protein-protein interaction by LC-MSMS
ORGANISM(S): Streptococcus pyogenes STAB901 
2020-04-15 | PXD012466 | Pride
Xlink Dsso Lc-msms 
Proteomicsrat myocardial left ventricular tissue proteins LC-MSMS
Rat left ventricular tissue LC-MSMS.Rat left ventricular tissue proteins from different groups were extracted and quantified using the BCA Protein Assay Kit (Thermo Fisher Scientific, USA). The proteins were then labeled with tandem mass tags (TMT). TMT6/10 (Pierce, USA) with different reporter ions...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-07-26 | PXD024641 | Pride
Rat Heart Lc-msms 
ProteomicsLC-MSMS of HEK 293T cells transfected with Flag-EV or Flag-ACE2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). Alongside investigation into the virology of SARS-CoV-2, understanding the host–virus dependencies are vital for the identification and rational design of effective antiviral t...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD034168 | Pride
Lc-msms Hek 293t Ace2 
ProteomicsCharacterization of SPSB1-regulated proteins following CRISPR APA engineering
Proteomics analysis was performed in 22Rv1, LNCaP-abl and BPH1 cells after transfection of 3'UTRCES-SPSB1 systems
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD071209 | Pride
Prostate cancer Crispr Alternative polyadenylation 
ProteomicsHost serum-derived flavivirus NS1 co-opts mosquito miRNA processing to suppress early immune defense
Flaviviruses pose growing global health threats and are transmitted by Aedes mosquitoes. Yet, how these viruses overcome early mosquito immunity remains unclear. Here, we reveal a cross-host immune evasion strategy in which the flavivirus NS1 protein, abundantly secreted into infected human serum, i...
ORGANISM(S): Aedes aegypti 
2026-08-18 | PXD067301 | Pride
Midgut Aedes aegypti Lc-ms/ms 
MetabolomicsAberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

OBJECTIVE: Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise relationships between the intestinal microbiome composition, uraemic toxins and rena...

2020-10-20 | MTBLS700 | MetaboLights
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