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TranscriptomicsTranscripts regulated by elevated DKF-2 (WT background)
Transcriptional profiling was used to determine why DKF-2 (protein kinase D) deficiency and surfeit caused hypersensitivity and resistance, respectively, to a bacterial pathogen (P. aeruginosa 14). The studies show that DKF-2 contributes to C. elegans innate immunity by inducing expression of >75 ge...
ORGANISM(S): Caenorhabditis elegans 
2009-01-12 | E-GEOD-12456 | biostudies-arrayexpress
ProteomicsCab45-dependent facilitation of insulin secretory granule biogenesis and its dysregulation in type 2 diabetes
Germanos M1*. Yau B1*. Taper M1. An Y1. Yeoman C1. Wilson A1. Cattin-Ortolá J2. Maslar D3. Tong J1. Naghiloo S1. Needham E4. Diaz-Vegas A4. Larance M1. Thomas H5. Seidah NG6. von Blume J7. James DE4. Thorn P1. Ailion M2. Asensio C3. Kebede MA1. 1 School of Medical Sciences, Charles Perkins Centre, ...
ORGANISM(S): Rattus rattus (Black rat) 
2024-12-02 | PXD052042 | Pride
Islet Cab45 Insulin 
UnknownThe Knight Alzheimer Research Imaging (KARI) dataset: a comprehensive multimodal resource for exploring aging, preclinical, and symptomatic Alzheimer disease pathology.
Not available
S-EPMC12637817 | biostudies-literature
UnknownComparison of cerebrospinal fluid, plasma and neuroimaging biomarker utility in Alzheimer's disease.
Not available
S-EPMC10950051 | biostudies-literature
UnknownPost-Translational Modifications Distinguish Amyloid-β Isoforms in Cerebral Amyloid Angiopathy and Alzheimer's Disease.
Not available
S-EPMC12745913 | biostudies-literature
ProteomicsMapping of the hSOX10 protein interactome in human melanoma
The transcription factor SOX10 is a central regulator of melanoma biology, influencing tumor initiation, progression, phenotypic plasticity, and therapeutic resistance. However, the molecular mechanisms underlying these diverse functions remain incompletely understood. To elucidate the protein-prote...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD067868 | Pride
Interactome mapping Mass spectrometry Miniturbo Melanoma Proximity-based biotinylation Protein-protein interactions Hsox10 
UnknownIdentification of Herpes Zoster-Associated Temporal Arteritis Among Cases of Giant Cell Arteritis.
Not available
S-EPMC5866091 | biostudies-literature
ProteomicsDefining the Structural Features of Complement-Active IgM: 3-state comparison
Immunoglobulin mu (IgM) is a class of mammalian antibodies that are critical for the early stages of adaptive immunity and are the most potent activators of the classical complement cascade. While the relationship between IgM and complement has been appreciated for decades, the structural transition...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-02 | PXD056897 | Pride
Igm Hdx-ms Antibody-antigen interaction 
ProteomicsDefining the Structural Features of Complement-Active IgM: 3-state comparison
Immunoglobulin mu (IgM) is a class of mammalian antibodies that are critical for the early stages of adaptive immunity and are the most potent activators of the classical complement cascade. While the relationship between IgM and complement has been appreciated for decades, the structural transition...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-14 | PXD056697 | Pride
Igm Hdx-ms Antibody-antigen interaction 
ProteomicsDefining the Structural Features of Complement-Active IgM: 3-state comparison of IgG
Immunoglobulin mu (IgM) is a class of mammalian antibodies that are critical for the early stages of adaptive immunity and are the most potent activators of the classical complement cascade. While the relationship between IgM and complement has been appreciated for decades, the structural transition...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-02 | PXD056918 | Pride
Igm Hdx-ms Antibody-antigen interaction Igg 
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