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ProteomicsOn-line desalting of sodium dodecyl sulfate in mass spectrometry
We tested here the ability of weak cation exchange (WCX) stationary phase to retain positively charged proteinaceous whilst negatively charged SDS molecules can be washed out from the capillary during on-line desalting. This novel chromatographic method named as online desalting of sodium dodecyl s...
ORGANISM(S): Homo sapiens (Human) 
2018-06-18 | PXD006035 | Pride
Sodium dodecyl sulfate Wcx Mass spectrometry Weak cation exchange Sds Lc-ms/ms 
ProteomicsOnline Weak Cation Exchange-HILIC × Reversed Phase LC UVPD-HRMS of intact HeLa Histones
Intact HeLa core Histones were analyzed using an online two-dimensional liquid chromatographic separation as well as one dimensional LC (RPLC and WCX-HILIC) coupled with UVPD-MS
ORGANISM(S): Homo sapiens (Human) 
2018-09-19 | PXD008978 | Pride
Histones Top-down proteomics Online 2dlc Uvpd 
UnknownIncreasing the Separation Capacity of Intact Histone Proteoforms Chromatography Coupling Online Weak Cation Exchange-HILIC to Reversed Phase LC UVPD-HRMS.
Not available
S-EPMC6220366 | biostudies-literature
UnknownIminodiacetic Acid (IDA) Cation-Exchange Nonwoven Membranes for Efficient Capture of Antibodies and Antibody Fragments.
Not available
S-EPMC8305546 | biostudies-literature
UnknownAnion-Facilitated Hydrogen-Deuterium Exchange as a Tool to Probe Weak Anion-Protein Interactions Responsible for Hofmeister Effects.
Not available
S-EPMC11873968 | biostudies-literature
UnknownWeak Spots in Semiconductor Nanoplatelets: From Isolated Defects Toward Directed Nanoscale Assemblies.
Not available
S-EPMC11798351 | biostudies-literature
ProteomicsProteome analysis reveals novel serum biomarkers for Henoch-Schönlein purpura in Chinese children
We performed proteomic profiling on serum samples from HSP patients and healthy children using an approach combining magnetic bead-based weak cation exchange and matrix-assisted laser desorption ionization-time of flight mass spectrometry. We next performed liquid chromatography-electrospray ionizat...
ORGANISM(S): Homo Sapiens 
PXD032897 |
ProteomicsRNA-Binding Motif protein 6 is a candidate serum biomarker for pancreatic cancer
Early diagnosis is crucial to improve outcomes for pancreatic cancer (PC) patients, however the lack of specific and validated biomarkers for the disease remains challenging. In this study, we analyzed the serum proteome of 12 PC patients and 76 healthy controls (HC), using magnetic bead-based weak ...
ORGANISM(S): Homo Sapiens 
PXD013626 |
UnknownMnCaTa2O7-A Magnetically Ordered Polar Phase Prepared via Cation Exchange.
Not available
S-EPMC10538500 | biostudies-literature
ProteomicsEvaluation of Protein Ion Relative Ratio Quantification in Top-down Electrospray Ionization–Mass Spectrometry Using Site-Specific Acetylated Recombinant Histone H3 Proteoforms
Electrospray ionization (ESI)-mass spectrometry (MS) provides a crucial platform for analyzing post-translationally modified proteins. With continuous advances in MS instruments and data analysis approaches, analyzing intact proteoforms using a “top-down” approach has become highly feasible. To quan...
ORGANISM(S): Homo sapiens (Human) 
2025-09-29 | PXD064777 | Pride
Proteoforms Top-down proteomics Histone h3 Quantitative proteomics Protein ion relative ratio 
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