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ProteomicsDARPin_study - Systemic analysis of tyrosine kinase signaling reveals a common adaptive response program in a HER2-positive breast cancer
Studying signaling networks downstream of HER2 inhibition
ORGANISM(S): Homo sapiens (Human) 
2019-01-28 | PXD011999 | Pride
Signaling Lcms 
ProteomicsEarly Signaling Dynamics of EGFR
Despite extensive study of the epidermal growth factor receptor (EGFR) signaling network, the immediate post-translational changes that occur in response to growth factor stimulation remain poorly characterized; as a result, the biological mechanisms underlying signaling initiation remain obscured. ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080800 | MassIVE
ProteomicsMultiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition
Major histocompatibility complex (MHC) class I peptides play a critical role in immune cell recognition and can trigger an antitumor immune response in cancer. Surface MHC levels can be modulated by anticancer agents, altering immunity. However, understanding the peptide repertoire response to treat...
ORGANISM(S): Homo sapiens (Human) 
2020-06-04 | PXD017407 | Pride
Lc-m 
ProteomicsTime-Dependent Proteome Study: Human colorectal tumor samples (0, 10, 30, 60 min)

The objective of the Time-Dependent Proteome Study was to evaluate changes in the proteome and phosphoproteome when there is a delay in freezing tissues following sample (tumor) excision. The biospecimens used are from snap-frozen colon adenocarcinoma core biopsy punches.

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-28 | MSV000084243 | MassIVE
UnknownPhotosynthetic and Growth Responses in a Pioneer Tree (Japanese White Birch) and Competitive Perennial Weeds (Eupatorium sp.) Grown Under Different Regimes With Limited Water Supply to Waterlogging.
Not available
S-EPMC8959217 | biostudies-literature
ProteomicsImmunopeptidomics reveals determinants of Mycobacterium tuberculosis antigen presentation on MHC class I (DDA data)
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is a leading cause of infectious disease mortality worldwide for which no sufficiently protective vaccine exists. CD8+ T cells contribute to protective immunity to TB, but the antigenic targets presented on MHC-I by macrophages infected ...
ORGANISM(S): Mycobacterium tuberculosis H37Rv Homo sapiens (Human) 
2023-04-24 | PXD037837 | Pride
Macrophage Human Tuberculosis Vaccines Infectious disease Immunopeptidomics Phagocyte Immunopeptidome Mhc-i Tb 
ProteomicsLimiting the buffer function of HSP90 enhances tumor immunogenicity
MC38 cells were treated with HSP90 inhibitor and antigen repertoires were analyzed via mass spectrometry.
ORGANISM(S): Mus musculus (Mouse) 
2019-06-26 | PXD009542 | Pride
Hsp90 Peptides Antigens 
ProteomicsDifferentially embedded glioblastoma tumor protein quantitation
Glioblastoma multiforme (GBM) is the most aggressive malignant primary brain tumor with a dismal mean survival even with the current standard of care. Although in vitro cell systems can provide mechanistic insight into the regulatory networks governing GBM cell proliferation and migration, clinical ...
ORGANISM(S): Homo sapiens (Human) 
2014-07-09 | PXD001038 | Pride
Glioblastoma Quantitation Protein expression Itraq Tumor 
ProteomicsTargeted exercise enhances functional integration of engineered muscle grafts after volumetric muscle loss
Damage that affects large volumes of skeletal muscle tissue can severely impact health, mobility, and quality-of-life. Efforts to restore muscle function by implanting engineered grafts at the site of damage have demonstrated limited restoration of force production. Various forms of mechanical and b...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD039237 | Pride
Engineered muscle graft Muscle phosphoproteomics Volumetric muscle loss 
ProteomicspathMHC: a workflow to selectively target pathogen-derived MHC peptides in discovery immunopeptidomics experiments for vaccine target identification
Neutrophils have emerged as diverse regulators of tissue states, displaying functions in both the resolution and promotion of tissue inflammation. While neutrophils have widely been associated with tumor promotion, immune suppression, and poor patient outcome, we provide evidence to support direct t...
ORGANISM(S): Mycobacterium tuberculosis Mycobacterium smegmatis Homo sapiens (Human) 
2025-07-08 | PXD055726 | Pride
Bacteria Mycobacterium tuberculosis Vaccines Tuberculosis Mhc Immunopeptidomics 
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