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ProteomicsDeep Succinylproteomics of Brain Tissues of Intracerebral Hemorrhage with inhibition of Toll-like receptor 4 signaling
The details of Toll-like receptor (TLR) 4 signaling affects protein succinylation in intracerebral hemorrhage (ICH) brains remains completely unclear. In this study, we constructed mice ICH models to investigate the changes in ICH-associated brain protein succinylation with the treatment of TLR4 ant...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-03 | PXD025622 | Pride
Intracerebral hemorrhage  brain injury  succinylation  toll-like receptor 4 
TranscriptomicsDynamic profile of gene expression in rice panicle under high temperature
To comprehend the profile of rice gene expression at reproductive stage under high temperature, Agilent 4M-CM-^W44k rice oligo microarray experiments were carried out using rice panicle of developmental stage 7-9 at 0min, 20min, 1hr, 2hr, 4hr, and 8hr after the treatment of 40 degree centigrade, and...
ORGANISM(S): Oryza sativa 
2012-11-28 | E-GEOD-38665 | biostudies-arrayexpress
MetabolomicsJasmonate-mediated stomatal closure under elevated CO2 revealed by time-resolved metabolomics
Foliar stomatal movements are critical for regulating plant water loss and gas exchange. Elevated carbon dioxide (CO2) levels are known to induce stomatal closure. However, the current knowledge on CO2 signal transduction in stomatal guard cells is limited. Here we report metabolomic responses of Br...
2017-04-25 | MTBLS312 | MetaboLights
ProteomicsComparative physiological and proteomic analysis reveals different involvement of proteins during artificial aging of Siberian wildrye (Elymus sibiricus L.) seeds
In total, 5134 protein groups were identified, among which 4169 proteins were quantified. The fold-change cutoff was set when proteins with quantitative ratios above 1.3 or below 1/1.3 and P value<0.05 are deemed significant. Among the quantified proteins, 70 proteins are up-regulated and 104 protei...
ORGANISM(S): Elymus sibiricus 
2021-09-09 | PXD021552 | Pride
Seed aging Reactive oxygen species Isobaric tandem mass tag labeling Parallel reaction monitoring Siberian wildrye 
ProteomicsSupercharging-Enhanced nDIA-MS Enables Global Profiling of Drug-Induced Proteome Solubility Shifts (solubility proteomics)
Mass spectrometry (MS)-based proteomics has become indispensable for high-throughput quantitation of protein expression. However, protein function is regulated by a variety of factors beyond abundance alone. Here, we optimized narrow-window, data-independent ac-quisition (nDIA) MS with 3% DMSO as a ...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD064185 | Pride
Ml-792 Proteome Solubility shift Mg132 
ProteomicsSupercharging-Enhanced nDIA-MS Enables Global Profiling of Drug-Induced Proteome Solubility Shifts (co-solvent)
Mass spectrometry (MS)-based proteomics has become indispensable for high-throughput quantitation of protein expression. However, protein function is regulated by a vari-ety of factors beyond abundance alone. Here, we optimized narrow-window, data-independent acquisition (nDIA) MS with 3% DMSO as a ...
ORGANISM(S): Homo sapiens (Human) 
2026-01-11 | PXD064180 | Pride
Mnba Dmso Supercharging Ndia-ms 
ProteomicsProteomic Stable Isotope Probing of Cecal Microbiota Using U ¹³C Glucose Under Anaerobic Conditions
This study applies proteomic stable isotope probing (proteomic SIP) to profile microbial protein synthesis during anaerobic incubation with 100% U ¹³C glucose. Cecal microbiota were cultured in deoxygenated M9 medium supplemented with 0.3 g L⁻¹ sodium thioglycolate, with U ¹³C glucose. Following inc...
ORGANISM(S): gut metagenome 
2026-09-12 | PXD075725 | Pride
Proteomic sip  u ¹³c glucose  ¹³c labeling  anaerobic incubation  m9 medium  mouse cecal microbiota  metaproteomics  nanolc  orbitrap fusion  dda  fasp  sipros 5  mgnify microbiome database 
ProteomicsSuccinylation profiles of brain injury after intracerebral hemorrhage
Protein posttranslational modifications (PTMs) has been shown to regulate biological processes of human diseases via expanding the genetic code and for regulating cellular pathophysiology, however, the system-wide changes at the PTMs levels in ICH brain remains little known. Given that succinylation...
ORGANISM(S): Mus musculus (Mouse) 
2021-10-29 | PXD025621 | Pride
Intracerebral hemorrhage  brain injury  succinylation 
MetabolomicsThe Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism
The overuse of antibiotics in animal agriculture and medicine has caused a series of potential threats to public health. Macleaya cordata is a medicinal plant species from the Papaveraceae family, providing a safe resource for the manufacture of antimicrobial feed additive for livestock. The active ...
2017-04-24 | MTBLS435 | MetaboLights
ProteomicsOptimization of ultra fast nDIA proteomics approach
Rapid and comprehensive analysis of complex proteomes across large sample sets is essential to fulfill the potential of systems biology. We present a novel mass spectrometry (MS) method that integrates narrow-window data-independent acquisition (nDIA) with short-gradient micro-flow chromatography, e...
ORGANISM(S): Homo sapiens (Human) 
2026-01-14 | PXD055919 | Pride
Short gradient Proteomics Hela Ultra-fast Ndia 
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