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MicroRNAs (miRNAs) are non-coding molecules involved in post-transcriptional gene regulation that have been shown to modulate tumor cell proliferation and apoptosis and to act as oncogenes or tumor-suppressor genes. Although miRNAs have been linked to tumor progression, the connection between tumor-...
ORGANISM(S): Homo sapiens 
An integrative proteotranscriptomics approach to uncover the transcriptional and post-transcriptional targets of the disintegrin metalloproteinase ADAM9, a sheddase that has been implicated in solid tumors, autoimmunity, inflammatory diseases and COVID-19. This systematic approach revealed signaling...
ORGANISM(S): Homo sapiens (Human) 
2026-04-13 | PXD059109 | Pride
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
Paneth cells are defensive cells in the intestinal tract, which secrete niche factors and antimicrobial peptides (AMPs) to maintain the small intestinal stem cell niche and immune homeostasis. Here, we show that Vestigial-like family member 4 (VGLL4) plays a pivotal role in maintaining small intesti...
2026-03-12 | MTBLS10456 | MetaboLights
In the current study, the RF model of the rat was established, and RNA-sequencing and real-time polymerase chain reaction (qRT-PCR) experiments were implemented. Subsequently, cell apoptosis and proliferation were carried out. Finally, the iTRAQ proteomics analyses were carried out for the samples.
ORGANISM(S): Homo Sapiens 
2022-10-31 | PXD037827 |
we conducted immunoprecipitation (IP) in UMUC3 and T24 cells using FKBP10 and Flag antibodies, followed by mass spectrometry analysis.
ORGANISM(S): Homo Sapiens 
2024-07-20 | PXD054092 |
To clarify our hypothesis and investigate the functional role of Oo-Mv in folliculogenesis, we isolated the ZP containing Oo-Mv from oocytes and performed mass spectrometry (MS) analysis to identify potential regulators of the formation of Oo-Mv.
ORGANISM(S): Mus Musculus 
2021-03-23 | PXD024931 |
Phosphorylation sites identified at the C-terminus of mGlu5 by mass spectrometry analysis
ORGANISM(S): Homo Sapiens 
2026-04-01 | PXD076479 |
In patients with hepatocellular carcinoma (HCC) meeting the Milan criteria, liver transplantation (LT) is an effective therapy. This study aims to define the survival-related molecular biological features helping precisely identifying the patients with HCC beyond the Milan criteria who have acceptab...
ORGANISM(S): Homo Sapiens 
2025-02-24 | PXD061119 |
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