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ProteomicsS-Nitrosylation-mediated dysfunction of TCA cycle enzymes in synucleinopathy studied in postmortem human brains and hiPSC-derived neurons
Here, we used a method, SNO trapping by triaryl phosphine (SNOTRAP), combined with mass spectrometry, to identify SNO-proteins present in post-mortem brain samples. Following analysis of SNO-proteins in samples of 11 human brains from patients LBD and controls, we detected 943 SNO-proteins and 1,552...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD036703 | Pride
Lbd Human brain Snotrap 
UnknownComplete chloroplast genome sequence of Dendranthema zawadskii Herbich.
Not available
S-EPMC8245063 | biostudies-literature
TranscriptomicsTranscription profiling by array of Drosophila fed methamphetamine
Methamphetamine can trigger dopamine releasing in human brain, now used as abuse drug. Some studies have shown that specific genes and proteins responded to, methamphetamine, but little is known about the overall omic response of organisms to this illicit substance. Here we demonstrate that Drosophi...
ORGANISM(S): Drosophila melanogaster 
2010-10-30 | E-GEOD-16198 | biostudies-arrayexpress
ProteomicsAlzheimer’s Disease (AD) and Lewy Body Dementia (LBD): Detection of S-Nitrosylation in Key Proteins in Human, Post-mortem Brain Samples
FAD and Lewy Body Dementia (LBD): Detection of S-Nitrosylation in Key Proteins in Human, Post-mortem Brain Samples
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD020945 | Pride
Lbd Ad Lc-ms2 
UnknownUltrafast excited state dynamics and light-switching of [Ru(phen)2(dppz)]2+ in G-quadruplex DNA.
Not available
S-EPMC9814642 | biostudies-literature
TranscriptomicsTranscription profiling of mouse hematopoietic cells at different differentiation stages: hematopoietic stem cells (HSCs), progenitor cells (HPCs), and granulocytes somatic cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer
Since the creation of Dolly, the first sheep cloned via somatic cell nuclear transfer (SCNT), in 1997, more than a dozen species of mammals have been cloned using this technology. One hypothesis for the limited success of cloning via SCNT (1-5%) is that the clones are likely derived from adult stem...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-5677 | biostudies-arrayexpress
UnknownBinding Interactions of Zinc Cationic Porphyrin with Duplex DNA: From B-DNA to Z-DNA.
Not available
S-EPMC5979451 | biostudies-literature
ProteomicsNuclear polysaccharides maintain H3K9me3-heterochromatin and genomic stability
Polysaccharides are traditionally confined to the cell surface and extracellular space, whereas their nuclear roles remain unclear. Here, we show that N-glycans are present in the nucleus and modify inner nuclear membrane (INM) proteins across multiple cell types. Disruption of INM protein N-glycosy...
ORGANISM(S): Mus Musculus 
2025-12-30 | PXD072505 |
ProteomicsLC-MS/MS identification and sequence analysis of ACE inhibitory peptides derived from bovine hemoglobin
This project contains raw MS data and database search files for the identification and sequence analysis of ACE inhibitory peptides derived from bovine hemoglobin using LC-MS/MS. The data includes original mass spectrometry files and corresponding search results for peptide identification and sequen...
ORGANISM(S): Bos Taurus 
2026-03-27 | PXD076229 |
ProteomicsSerum proteomics identify biomarkers associated with the pathogenesis of idiopathic pulmonary fibrosis
This serum proteomic profile provides rigorous evidence that enables understanding of the heterogeneity of IPF and protein alterations that could help in its diagnosis and treatment decisions.
ORGANISM(S): Homo Sapiens 
2024-05-16 | PXD052329 |
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