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UnknownComparative analyses of fecal microbiota in Chinese isolated Yao population, minority Zhuang and rural Han by 16sRNA sequencing.
Not available
S-EPMC5773753 | biostudies-literature
GenomicsMNase digestion-sensitive nucleosomes in Saccharomyces cerevisiae
The structural complexity of nucleosomes underlies their functional versatility. Here we report a new type of complexity – nucleosome fragility, manifested as high sensitivity to micrococcal nuclease, in contrast to the common presumption that nucleosomes are similar in resistance to MNase digestio...
ORGANISM(S): Saccharomyces cerevisiae 
2011-01-24 | E-GEOD-26412 | biostudies-arrayexpress
UnknownClinical efficacy and regulatory mechanisms of Shi Pi Zeng Ye formula in treating functional constipation comorbid with depression: integrating clinical observation, mass spectrometry, bioinformatics, and molecular docking.
Not available
S-EPMC12404943 | biostudies-literature
UnknownAnti α-enolase antibody is a novel autoimmune biomarker for unexplained recurrent miscarriages.
Not available
S-EPMC6444073 | biostudies-literature
ProteomicsA sensitive and cost-effective approach for tyrosine phosphoproteome analysis based on SH2 superbinder
Albeit much less abundant than Ser/Thr phosphorylation (pSer/pThr), Tyr phosphorylation (pTyr) is considered a hallmark in cellular signal transduction. However, its analysis remains a challenge. The conventional immunopurification (IP) approach using antibodies pan-specific to pTyr sites is known t...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2017-08-29 | PXD005838 | Pride
Lc ms/ms Sh2 superbinder Ptyr phosphoproteome 
ProteomicsFormula Q attenuates letrozole-induced polycystic ovary syndrome through modulating multiple pathways in rat
In this research, we investigated the molecular mechanisms and signaling pathways of Formula Q attenuating PCOS using a Tandem Mass Tag (TMT) proteomics approach, bioinformatics analyses and molecular biological technology. This study aimed to comprehensively characterize the multiple molecular mech...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-05-25 | PXD057910 | Pride
Multiple pathways Formula q Proteomics Traditional chinese medicine Pcos 
GenomicsEnvironmental enrichment modulates 5-hydroxymethylcytosine dynamics in hippocampus
Gene-environment interactions mediated at the epigenetic level may provide an initial step in delivering an appropriate response to environmental changes. 5-hydroxymethylcytosine (5hmC), a DNA base derived from 5-methylcytosine (5mC), accounts for ~40% of modified cytosine in brain and has been impl...
ORGANISM(S): Mus musculus 
2014-09-11 | E-GEOD-61194 | biostudies-arrayexpress
ProteomicsHuman LC-MS/MS for MBTPS1/S1P protein
To explore the molecular mechanism underlying the inflammatory symptoms, we set out to screen S1P interactors using Co-IP and liquid chromatography-tandem mass spectrometry (LC-MS/MS) and identified 29 potential candidates
ORGANISM(S): Homo sapiens (Human) 
2022-05-04 | PXD031064 | Pride
Human lc-ms/ms 
MetabolomicsThe Inhibition of B7H3 by 2-HG Accumulation Is Associated With Downregulation of VEGFA in IDH Mutated Gliomas
B7H3 (also known as CD276) is a co-stimulator checkpoint protein of the cell surface B7 superfamily. Recently, the function beyond immune regulation of B7H3 has been widely studied. However, the expression preference and the regulation mechanism underlying B7H3 in different subtypes of gliomas is ra...
2021-05-26 | MTBLS2692 | MetaboLights
UnknownVariants in the SNCA Locus Are Associated With the Progression of Parkinson's Disease.
Not available
S-EPMC6562243 | biostudies-literature
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