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MetabolomicsThe Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism
The overuse of antibiotics in animal agriculture and medicine has caused a series of potential threats to public health. Macleaya cordata is a medicinal plant species from the Papaveraceae family, providing a safe resource for the manufacture of antimicrobial feed additive for livestock. The active ...
2017-04-24 | MTBLS435 | MetaboLights
ProteomicsConotoxin Exploitation from Conus betulinus
Employing Conus betulinus as a representative, we sequenced and assembled the first Conus genome. After integration of multi-omics data, we provide novel insights into the genetic central dogma of conotoxins, assuming a number ratio of ~1:1:10s for genes/transcripts/peptides.
ORGANISM(S): conus betulinus 
2021-09-08 | PXD014892 | Pride
Conus  genome  conotoxins  multi-omics  transcript  proteomics  peptide 
ProteomicsLicorice Ameliorates Cisplatin-Induced Hepatotoxicity through Anti-apoptosis, Anti-oxidative Stress, Anti-inflammation, and Acceleration of Metabolism
Cisplatin (CP) is one of the most effective antitumor drugs in the clinic, but has serious adverse reactions, and its hepatotoxicity has not been fully investigated. Licorice (GC), a traditional herbal medicine, has been commonly used as a detoxifier for poisons and drugs, and may be an effective dr...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-11-27 | PXD021688 | Pride
Proteomics Hepatotoxicity Detoxification Cisplatin Licorice 
TranscriptomicsIdentification of Rhizome-Specific Genes by Genome-wide Differential Expression Analysis in Oryza longistaminata
The Oryza longistaminata is a perennial wild rice species with AA genome, which characterized by the presence of rhizomatous stem. The rhizomatousness trait in rice was previously identified quantitatively controlled by many genes, but the molecular mechanism related to the rhizome initiation and el...
ORGANISM(S): Oryza longistaminata 
2010-10-31 | E-GEOD-24228 | biostudies-arrayexpress
ProteomicsProteomic investigations of transcription factors critical in geniposide-mediated suppression of alcoholic steatosis and in overdose induced hepatotoxicity on liver
Geniposide mediated therapeutic effects and overdose-induced hepatotoxicity
ORGANISM(S): Rattus Rattus 
2019-08-12 | PXD014996 |
ProteomicsPick-up single-cell proteomic analysis for quantifying up to 3000 proteins in a tumor cell
The shotgun proteomic analysis is currently the most promising single-cell protein sequencing technology, however its identification level of ~1000 proteins per cell is still insufficient for practical applications. Here, we develop a pick-up single-cell proteomic analysis (PiSPA) workflow to achiev...
ORGANISM(S): Homo Sapiens 
2023-10-30 | PXD041966 |
ProteomicsSIRT5 ameliorates cardiac fibrosis via PCK2 de-succinylation–mediated metabolic reprogramming in cardiac fibroblasts
WT and Sirt5-/- CFBs were stimulated with TGF-β1 (10 ng/mL) for 36 hours. Cells were harvested, snap-frozen, and stored at -80℃. The experiment was independently repeated six times at different time points. Cells from each replicate were pooled to yield more than 3 mg of protein per group. Pooled WT...
ORGANISM(S): Mus Musculus 
2025-11-15 | PXD070811 |
ProteomicsProtein differential profiling of OTUB1 knockout osteoblasts
This project is to figure out the differential proteins in control and OTUB1 knockout osteoblast cells
ORGANISM(S): Mus Musculus 
2023-01-17 | PXD039507 |
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