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ProteomicsYTHDF2 regulates self non-coding RNA metabolism to control TLR3 activation in Inflammation
To elucidate the roles of YTHDF2 in the UV response in Human Keratinocyte (HaCaT) cells, the YTHDF2 interactome was analyzed through immunoprecipitation using a YTHDF2-specific antibody. Control IgG served as a negative control in this study. The cells were treated with UVB at 20 mJ/cm², and one hou...
ORGANISM(S): Homo sapiens (Human) 
2025-09-10 | PXD059422 | Pride
U6 Cancer Ythdf2 Tlr3 Inflammation M6a Snrna Rna methylation Uvb 
ProteomicsO-GlcNAcylation of YTHDF2 antagonizes ERK-dependent phosphorylation and inhibits lung carcinoma
The intracellular O-linked N-acetylglucosamine (O-GlcNAc) glycosylation mediates many signal transduction events and regulates tumorigenesis. Previously the RNA N6-methyladenosine (m6A) reader, YTH (YT521-B homology) domain 2 (YTHDF2), has been shown to be O-GlcNAcylated on Ser-263 during Hepatitis ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD045137 | Pride
O-glcnac  m6a  c-myc  erk  lung carcinoma 
GenomicsYTHDF2 irCLIP-seq
YTHDF2 irCLIP-seq
PRJNA422164 | ENA
GenomicsAnti-YTHDF2 RIP-Seq to identify YTHDF2 target mRNAs in hippocampus
Anti-YTHDF2 RIP-Seq to identify YTHDF2 target mRNAs in hippocampus
PRJNA720917 | ENA
TranscriptomicsMicroarray data from YTHDF2-deficient pre-leukemic cells and control pre-leukemic cells
YTHDF2 is overexpressed in a broad spectrum of human acute myeloid leukemias (AML). To study the role of YTHDF2 in leukemia, c-Kit+ cells from foetal livers of Ythdf2fl/fl;Vav-iCre (Ythdf2CKO) and Ythdf2fl/fl (Ythdf2CTL) 14.5 dpc embryos were transduced with Meis1 and Hoxa9 oncogenes and serially re...
ORGANISM(S): Mus musculus 
2019-04-05 | E-MTAB-6783 | biostudies-arrayexpress
GenomicsAnti YTHDF2 RIP-seq to identify YTHDF2 target mRNAs in P0 mouse retinas
Anti YTHDF2 RIP-seq to identify YTHDF2 target mRNAs in P0 mouse retinas
PRJNA607064 | ENA
GenomicsYTHDF2 iCLIP in glioblastoma stem cells
YTHDF2 iCLIP in glioblastoma stem cells
PRJNA663772 | ENA
GenomicsZNF121 recruits YTHDF2 to modulate mRNA stability
ZNF121 recruits YTHDF2 to modulate mRNA stability
PRJEB101442 | ENA
GenomicsAnti-YTHDF1 and anti-YTHDF2 RIP-Seq to identify the target mRNAs for YTHDF1 and YTHDF2, respectively
Anti-YTHDF1 and anti-YTHDF2 RIP-Seq to identify the target mRNAs for YTHDF1 and YTHDF2, respectively
PRJNA643706 | ENA
TranscriptomicsMicroarray profiling of YTHDF2 deficient mouse oocytes
To study the role of the protein YTHDF2 during female gametogenesis, its gene was conditionally deleted in oocytes. Total RNA samples from YTHDF2 deficient GV and MII oocytes (and control oocytes) were subjected to array profiling.
ORGANISM(S): Mus musculus 
2018-02-12 | E-MTAB-5576 | biostudies-arrayexpress
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