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ProteomicsQuantitative tissue proteomics analysis of primary lung adenocarcinoma
In this study, we generated a quantitative lung tissue proteome dataset from lung adenocarcinoma and adjacent normal lung tissues by using iTRAQ labeling combined with 2D-LC-MS/MS. Based on pathway and network analyses, protein expression profiles released in the public Human Protein Atlas database,...
ORGANISM(S): Homo sapiens (Human) 
2016-05-12 | PXD004077 | Pride
Lung cancer  adenocarcinoma  lymph node metastasis  biomarkers  ero1l  nars  itraq 
ProteomicsIdentification of proteins interacting with the small GTPase Arl4D by liposome flotation assay and mass spectrometry
N-terminal myristoylation serves as an important modification for membrane insertion and concrete membrane anchoring of the small GTPases ADP-ribosylation factor (Arf) and ADP ribosylation factor-like (Arl). To simulate the binding topology of Arl4D on the membrane, we performed the liposome flotati...
ORGANISM(S): Homo sapiens (Human) 
2025-05-10 | PXD054952 | Pride
Erk2 Small gtpase arl4d Liposome flotation 
ProteomicsIdentification of potential self-interaction sites on golgin Imh1-C213 by cross-linking mass spectrometry
The golgins are long coiled-coil proteins involved in vesicular transport to the Golgi, a process that contributes to Golgi function and integrity. Previous studies have elucidated that their self-interaction and their interaction with small GTPase Arl1 are critical for their Golgi localization. Her...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-04-30 | PXD061125 | Pride
Golgin Golgi Dimer Cross-link Glycerol Imh1 
ProteomicsQuantitative phosphoproteomic analysis of human Arl4A upon fibronectin stimulation
The extracellular matrix (ECM) fibronectin (FN) not only provides the framework for cell invasion and deposition of collagens and other ECMs from wound studies, but also guide collective tumor migration during cancer progression. p21-activated kinase 1 (Pak1) and Arf-like (Arl) GTPase Arl4A have pre...
ORGANISM(S): Homo sapiens (Human) 
2022-07-29 | PXD032397 | Pride
Arf-like gtpase Hypk Arl4a Fibronectin Pak1 
ProteomicsIdentification and quantification of KPNA2 phosphorylation and interactome in response to hydrogen peroxide-induced oxidative stress
Karyopherin α 2 (KPNA2, importin α1) is involved in the nuclear import of proteins and participates in cellular processes and accumulates in the nucleus under cellular stresses including hydrogen peroxide-indeced oxidative stress via unknown mechanisms. We performed the immunoprecipitation assay and...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD051121 | Pride
Npm1 Hydrogen peroxide Silac Phosphorylation Kpna2 
ProteomicsIdentification of Golgin Imh1 phosphorylation residues under ER stress in yeast
The accumulation of misfolded proteins in the endoplasmic reticulum (ER) induces the unfolded protein response (UPR), which acts through various mechanisms to reduce ER stress. We previously found ER stress induced by tunicamycin (TM) treatment promotes the activation of small GTPase Arl1 and thereb...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-07-21 | PXD031562 | Pride
Snare transport Gtpase arl1 Imh1 Phosphorylation Er stress 
ProteomicsInvestigating the upstream signaling of Imh1 phosphorylation under ER stress in yeast
The accumulation of misfolded proteins in the endoplasmic reticulum (ER) induces the unfolded protein response (UPR), which acts through various mechanisms to reduce ER stress. We previously found ER stress induced by tunicamycin (TM) treatment promotes the activation of small GTPase Arl1 and thereb...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-07-21 | PXD031563 | Pride
Ire1 Snare transport Gtpase arl1 Imh1 Phosphorylation Er stress 
ProteomicsQuantitative proteomics reveals inflammatory signaling in golgin-97 knockout-mediated breast cancer progression
The Golgi apparatus serves as a central hub for trafficking, regulating the anterograde transport and modification of proteins and lipids, or recycling extracellular proteins via retrograde transport through endosomes. Several Golgi-localized proteins have been reported to be involved in regulating ...
ORGANISM(S): Homo sapiens (Human) 
2025-03-07 | PXD056499 | Pride
Breast cancer Golgin-97 Inflammatory Golgi Metastasis 
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
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