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ProteomicsPorcine LC-MSMS - Porcine Breast Extracellular Matrix Hydrogel for Spatial Tissue Culture
Porcine breast fatty extracellular matrix proetiens has been extracted after decellularization of fatty tissue with conventional method (PFT-1) using triton X-100 and sodium dodecyl sulfate and extracted with modified methods keeping natural protein in their natural condition using X-100, urea, thio...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2019-11-12 | PXD011011 | Pride
Breast Porcine Extracellular matrix proteins 
ProteomicsPorcine breast extracellular matrix hydrogel for spatial tissue culture
Porcine mammary fatty tissues represent an abundant source of biomaterial for generation of breast-specific extracellular matrix (ECM). Here we report the extraction of total ECM proteins from pig breast fatty tissues, the fabrication of hydrogel scaffolds from the extracted ECM proteins, the struct...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2019-11-12 | PXD010960 | Pride
Breast cancer Ecm Hydrogel Scaffold Porcine 3d culture 
ProteomicsProteome-Centric Cross-Omics Characterization and Integrated Network Analyses of Triple-Negative Breast Cancer
We undertook the first systemic proteomic study of a 90-case cohort of triple-negative breast cancer (TNBC) with a panoramic proteome view in quantification, phosphorylation, and DNA-binding capacity. Four integrative subtypes (iP-1-4) were stratified based on the proteome quantification profile and...
ORGANISM(S): Homo Sapiens 
2021-08-24 | PXD028102 |
UnknownNeoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): A Phase III Multicenter, Randomized, Open-Label Clinical Trial.
Not available
S-EPMC6145832 | biostudies-literature
ProteomicsTime- and dose-resolved proteome of PM2.5 exposure in rat model
this paper used Mass spectrometry, Fast-seq, and catTFRE to study the pattern of 6316 proteins as well as 387 Transcription factors associated with PM2.5 in both short-term and long-term rat injury models.
ORGANISM(S): Rattus Norvegicus 
2020-05-27 | PXD019404 |
ProteomicsIdentification of an unrecognized circRNA associated with the development of renal fibrosis
In the current study, the RF model of the rat was established, and RNA-sequencing and real-time polymerase chain reaction (qRT-PCR) experiments were implemented. Subsequently, cell apoptosis and proliferation were carried out. Finally, the iTRAQ proteomics analyses were carried out for the samples.
ORGANISM(S): Homo Sapiens 
2022-10-31 | PXD037827 |
ProteomicsRSDR, a Novel Potential Biomarker, Protects Against AKI by Interacting with hnRNPK to Regulate DHODH-Mediated Ferroptosis
Molecular analyses—including RNA immunoprecipitation, pull-down assays, mass spectrometry, and chromatin immunoprecipitation sequencing—demonstrated that RSDR and hnRNPK stabilize each other, forming a positive feedback loop that amplifies DHODH expression.
ORGANISM(S): Mus Musculus 
2025-03-19 | PXD062047 |
ProteomicsUltradeep N-glycoproteome Atlas of Mouse Reveals Spatiotemporal Signatures of Brain Aging and Neurodegenerative Diseases
The current depth of site-specific N-glycoproteomics is insufficient to fully characterize glycosylation events in biological samples. Herein, we achieved an ultradeep and precision analysis of the N-glycoproteome of mouse tissues by integrating multiple workflows. The largest N-glycoproteomic datas...
ORGANISM(S): Mus Musculus 
2025-03-04 | PXD061436 |
ProteomicsPhospho-proteomics enables classification of cancer subtypes and nomination of druggable kinases for individual patients of diffuse-type gastric cancer
The diffuse-type gastric cancer (DGC) constitutes a subgroup of gastric cancer with poor prognosis and no effective molecular therapies. Here, we report a phosphoproteomic landscape of DGC derived from 83 tumors together with their nearby tissues. Based on phosphorylation, DGC could be classified in...
ORGANISM(S): Homo Sapiens 
2020-03-31 | PXD018293 |
TranscriptomicsEffect of imatinib on philadelphia chromosome positive acute lymphoblastic leukemia
The Philadelphia chromosome (Ph) encodes the oncogenic BCR-ABL1 tyrosine kinase, which defines a subset of acute lymphoblastic leukemia (ALL) with a particularly unfavorable prognosis. In this study, the tyrosine kinase inhibitor imatinib was used for pharmacological inhibition of BCR-ABL1. Gene exp...
ORGANISM(S): Homo sapiens 
2010-09-10 | E-GEOD-23743 | biostudies-arrayexpress
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