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MetabolomicsRP-based analysis of human faecal samples using the ZenoTOF 7600

This study contains replicated measurements of a reference human fecal sample from BioIVT. It serves as test and training data for metabolite annotation.

2025-08-07 | MTBLS8356 | MetaboLights
ProteomicsSpectral quality guided optimization of hybrid EAciD fragmentation on the ZenoTOF 7600 system
Systematically optimized N-glycoproteomics method combining EAD and CID on the ZenoTOF 7600. Several dynamic CID parameters were optimized, next EAD was added using different kinetic energy values. Optimization was performed on glycopeptide enriched human plasma. After optimization, the method was ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-07-15 | MSV000098519 | MassIVE
ProteomicsElectron-Activated Dissociation and Collision-Induced Dissociation Glycopeptide Fragmentation for Improved Glycoproteomics
Protein glycosylation is a critical PTM for the stability and biological function of many proteins, but full characterisation of site-specific glycosylation of proteins remains analytically challenging. Collision induced dissociation (CID) is the most common fragmentation method used in LC-MS/MS wor...
ORGANISM(S): Homo sapiens (Human) 
2024-07-04 | PXD050173 | Pride
Cid Glycopeptide Ead Zenotof 7600 
ProteomicsData-Independent Acquisitions Uncover Kidney Proteome Remodeling during Ischemic Reperfusion Kidney Injury using a Fast-scanning ZenoTOF 7600
Acute kidney injury (AKI) manifests as a major health concern particularly for the elderly and understanding related proteome changes is critical for prevention and development of novel therapeutics to recover kidney function, and to mitigate the susceptibility for recurrent AKI, or development of c...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-11-23 | MSV000090777 | MassIVE
ProteomicsData for Cross-platform Construction of Comprehensive Proteomic Database for Human Corneal Epithelial Cell
Comprenhensive proteomic analysis of HCEC using Trapped Ion Mobility Spectrometry Time-of-Flight Pro2, Orbitrap Fusion Lumos and ZenoTrap Time-of-Flight 7600 Mass Spectrometer
ORGANISM(S): Homo sapiens (Human) 
2024-11-03 | PXD055275 | Pride
Fuaion Hcec Timstof Zenotof 
ProteomicsData for Cross-platform Construction of Comprehensive Proteomic Database for Human Corneal Epithelial Cell
Comprenhensive proteomic analysis of HCEC using Trapped Ion Mobility Spectrometry Time-of-Flight Pro2, Orbitrap Fusion Lumos and ZenoTrap Time-of-Flight 7600 Mass Spectrometer
ORGANISM(S): Homo sapiens (Human) 
2025-03-24 | PXD059451 | Pride
Timstof Proteome Orbitrap Zenotof Human corneal epithelial cell 
ProteomicsEvaluation of the carrier proteome limit on a ZenoTOF instrument
This analysis sought to evaluate the carrier proteome limits on a SCIEX 7600 ZenoTOF mass spectrometer. A 9 channel TMTPro digest standard previously described in Orsburn, et al., Nature Communcations 2022 was used. . Briefly, a K562 human peptide digest standard (Promega) and E.coli peptide standar...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) Homo Sapiens (ncbitaxon:9606) 
2024-02-08 | MSV000094044 | MassIVE
ProteomicsLocalization and Quantification of Post-Translational Modifications of Proteins Using Electron Activated Dissociation Fragmentation on the ZenoTOF 7600 System
Protein post-translational modifications (PTMs) are crucial and dynamic players in a large variety of cellular processes and signaling, and proteomic technologies have emerged as the method of choice to profile PTMs. However, these analyses remain challenging due to potential low PTM stoichiometry, ...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-04-16 | MSV000091722 | MassIVE
ProteomicsTriple acquisition mass spectrometry (TRAM) combining targeted and non-targeted metabolomics in a single run
Data was acquired in TRAM (DDA+MRM), DDA-only, and MRM-only mode on a ZenoTOF 7600 with alkaline HILIC separation.
ORGANISM(S): Metabolite Standards Homo Sapiens (ncbitaxon:9606) 
2024-05-08 | MSV000094712 | MassIVE
ProteomicsA universal peptide and any peptidoform spectrum annotator for mass spectrometry-based proteomics
Example dataset for Annotator tool. Data includes: - the top-down data of Fab of Herceptin, summed and deconvoluted, measured on Eclipse; - the bottom-up data of O-glycosylation of human colostrum IgA, measured on ZenoTOF 7600 using EAD; - the bottom-up data of N-glycosylation of human plasma, measu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-01-13 | MSV000096837 | MassIVE
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