Sort   by:  
 Page size 
TranscriptomicsAssociation of genes regulated by Ezh2 and trimethylation of histone 3 lysine 27
Differentiation of naïve CD4+ T cells into effector (Th1, Th2 and Th17) and induced regulatory (iTreg) T cells requires lineage-specifying transcription factors and epigenetic modifications that allow appropriate repression or activation of gene transcription. The epigenetic silencing of cytokine ge...
ORGANISM(S): Mus musculus 
2014-08-04 | E-GEOD-57500 | biostudies-arrayexpress
UnknownGene Expression Profiling Reveals Aberrant T-cell Marker Expression on Tumor Cells of Waldenstrom's Macroglobulinemia.
Not available
S-EPMC6320275 | biostudies-literature
ProteomicsPeritoneal Cell-Derived Exosomes: Novel Mediators of T Cell Activation and Vaccine Potency in Fish
Exosomes are small extracellular vesicles that play significant roles in cell communication and immune modulation. When considering adaptive immunity, exosomes have been proposed to be involved in T and B cell development, antigen presentation, as well as the cross-presentation of antigens. While th...
ORGANISM(S): Paralichthys olivaceus 
2026-04-06 | PXD059066 | Pride
Vaccine potency Antibody response T-cell activation  fish Exosomes 
TranscriptomicsTranscription profiling of human Waldenstroms macroglobulinemia CD19+ WM B cells (WM-BC) and CD138+ WM plasma cells (WM-PC) with those of normal CD19+ peripheral blood B cells (PB-BC), tonsil-BC (T-BC), CD138+ T-PC and bone marrow PC (N-PC) reveals biological insights into its pathophysiology
Waldenströms macroglobulinemia (WM) is a rare lymphoproliferative disorder with apparent morphologic and immunophenotypic heterogeneity and its origins are still poorly understood. In this study, using Gene-Expression Profiling (GEP), we compared the global mRNA expression patterns of CD19+ WM B cel...
ORGANISM(S): Homo sapiens 
2008-12-05 | E-GEOD-9656 | biostudies-arrayexpress
ProteomicsCIS deficiency intensifies GM-CSF signaling to polarize alternative activated macrophages
GM-CSF paradoxically possesses ability to differentiate both classically activated macrophages (MØs) with dominant proinflammatory function (M1-like MØs) and alternative activated MØs with strong immunosuppressive function (M2-like MØs). The intrinsic regulatory mechanism responsible for functional ...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-21 | PXD018390 | Pride
Cis Gm-csf Macrophage polarization Tumour immunity 
UnknownIncreased TOX expression associates with exhausted T cells in patients with multiple myeloma.
Not available
S-EPMC8895562 | biostudies-literature
UnknownComparative metabolomics reveals the metabolic variations between two endangered Taxus species (T. fuana and T. yunnanensis) in the Himalayas.
Not available
S-EPMC6142684 | biostudies-literature
UnknownSplit tolerance permits safe Ad5-GUCY2C-PADRE vaccine-induced T-cell responses in colon cancer patients.
Not available
S-EPMC6477737 | biostudies-literature
ProteomicsHighly Active CAR T Cells that Bind to a Juxta-Membrane Region of Mesothelin and are Not Blocked by Shed Mesothelin
Identification of the major protease sites in MSLN and preparation of a monoclonal antibody, 15B6, that binds next to cell membrane at the protease sensitive region and inhibits MSLN shedding. Mab 15B6 makes very active CAR-T cells whose activity is not blocked by shed MSLN. The 15B6 CAR-T cells hav...
ORGANISM(S): Homo sapiens (Human) 
2022-04-13 | PXD033137 | Pride
Cancer Antibody Ovarian cancer Immunotherapy Pancreatic cancer 
UnknownKinetics of T lymphocyte subsets and B lymphocytes in response to immunostimulants in flounder (Paralichthys olivaceus): implications for CD4+ T lymphocyte differentiation.
Not available
S-EPMC7429840 | biostudies-literature
Sort   by:  
 Page size