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Recurrent miscarriage (RM) is the occurrence of repeated pregnancies that end in miscarriage of the fetus before 20 weeks of gestation. Recurrent miscarriages affect about 1-2% of couples trying to conceive; however, mechanisms leading to this complication are largely unknown. Our previous studies u...
ORGANISM(S): Homo sapiens (Human) 
2021-07-30 | PXD023849 | Pride
Patent ductus arteriosus (PDA) is the third most common congenital heart disease and resulted from the persistence of ductal patency after birth. Ductus arteriosus closure involves functional and structural remodeling, controlled by many factors. The closure-related human plasma proteins are unknown...
ORGANISM(S): Homo sapiens (Human) 
2018-11-30 | PXD008568 | Pride
Acute myocardial infarction (AMI) is one of the leading causes of death. It is particularly important to predict malignant ventricular arrhythmia (MVA) timely and accurately in patients with AMI. This study aimed to explore biomarkers and to reveal possible mechanisms of MVA in AMI for clinical diag...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD041535 | Pride
Lysine propionylation modification (Kpr) plays an important role in the pathogenesis of several cardiovascular diseases, but the role of Kpr in postoperative atrial fibrillation (POAF) is unclear. Here, we established an atlas of proteomics and propionylation proteomics in the atrial appendage tissu...
ORGANISM(S): Homo sapiens (Human) 
2025-08-11 | PXD059607 | Pride
We performed 4D-labelfree quantitative proteomics analysis of right atrial appendage tissues from 5 patients with atrial fibrillation (AF) and 5 patients with sinus rhythm (SR) after CABG. A total of 2179,559 spectrums and 48,047 peptides were detected by mass spectrometry. Further, we identified 50...
ORGANISM(S): Homo sapiens (Human) 
2025-08-11 | PXD059685 | Pride
Purpose: Damage to the uterosacral ligaments is an important contributor to uterine and vaginal prolapse. The aim of this study was to identify differentially expressed proteins in the uterosacral ligaments of women with and without pelvic organ prolapse and analyze their relationships to cellular...
ORGANISM(S): Homo sapiens (Human) 
2018-12-10 | PXD011467 | Pride

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). Due to M. leprae's narrow host range and an inability to be cultured in vitro, the biological investigation of this disease has been difficult. Host genetic factors have been ...

Introduction Previous studies have demonstrated that exposed to the initial suboptimal intrauterine environment of gestational diabetes mellitus (GDM) may increase risk of cardiovascular disease in adulthood. Methods In order to investigate the underlying mechanisms involved in the increased risk o...
ORGANISM(S): Homo Sapiens 
2021-03-20 | PXD024892 |
One of our previous studies has shown that there are two IgY subclasses (termed IgY1 and IgY2) in the serum of snake Elaphe taeniura, and both subclasses are expressed as full-length and shortened isoforms (IgY1-L, IgY2-L,IgY1-S, and IgY2-S). Using 2-DE and LC-MS/MS, we detected IgY1-L, IgY2-L,IgY1-...
ORGANISM(S): Elaphe Taeniura 
2024-08-23 | PXD055127 |
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