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MetabolomicsDiscovery and validation of potential serum biomarkers for heart failure by untargeted metabolomics

Detection of biomarkers was extremely important for the early diagnosis, prognosis and therapy optimization of diseases. The purpose of this study was to investigate the differences in serum metabolites between patients with heart failure (HF) and healthy controls (HC), and to diagnose HF qualita...

2025-07-18 | MTBLS9586 | MetaboLights
ProteomicsDPF3 and SNIP1 IP-MS in 786-O cells
In this project, we performed DPF3 and SNIP1 immunoprecipitation followed by mass spectrometry analysis to identify their interacting partners.
ORGANISM(S): Homo sapiens (Human) 
2022-08-22 | PXD033421 | Pride
Dpf3 Snip1 
ProteomicsIdentification of E2f1 interactors during early embryonic development in Xenopus tropicalis
In this project, we performed E2f1 immunoprecipitation followed by mass spectrometry analysis to identify its interacting partners during early embryonic development in Xenopus tropicalis.
ORGANISM(S): Xenopus tropicalis 
2025-12-01 | PXD051084 | Pride
Early embryonic development E2f1 Xenopus tropicalis 
GenomicsDynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells
We investigated genome-wide nucleosome coverage and histone methylation occupancies in somatic MEFs, intermediate pre-iPSCs and fully reprogrammed iPSCs. We found that nucleosome occupancies increased in promoter regions and decreased in intergenic regions in pre-iPSCs and then recover to an interme...
ORGANISM(S): Mus musculus 
2015-12-13 | E-GEOD-60627 | biostudies-arrayexpress
ProteomicsEffective Enrichment Strategy Using Boronic Acid Functionalized Mesoporous Graphene Silica Composites for Intact Glycopeptide Analysis in Human Serum
The heterogeneity and low abundance of protein glycosylation present challenging barriers to the analysis of intact glycopeptides, which is key to comprehensively understanding the role of glycosylation in an organism. Efficient and specific enrichment of intact glycopeptides could help greatly with...
ORGANISM(S): Human 
2021-04-28 | MSV000087324 | MassIVE
ProteomicsIn-depth Proteomics and Phosphoproteomics Reveal Biomarkers and Molecular Pathways of Chronic Intermittent Hypoxia in Mice
Obstructive sleep apnea (OSA) syndrome is characterized by Chronic Intermittent Hypoxia (CIH). In this study, we employed Data-independent acquisition (DIA) Mass Spectrometry to conduct comprehensive proteomic and phosphoproteomic profiling of a murine model subjected to Chronic Intermittent Hypoxia...
ORGANISM(S): Homo Sapiens 
2024-07-08 | PXD053746 |
ProteomicsNCI60 proteome by PCT-SWATH - Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines
We obtained quantitative analysis of the NCI-60 cell panels using pressure cycling technology (PCT) and SWATH-MS. Each cell was analyzed in duplicate. The data were analyzed using a cell line SWATH assay library and OpenSWATH, followed by SWATH-expert refinement.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-07-29 | MSV000085848 | MassIVE
ProteomicsCircadian proteome atlas of wild-type and Per1-/-/Per2-/- mice models across eight organs
a circadian proteome atlas of eight organs, namely suprachiasmatic nucleus (SCN), hypothalamus (HPOA), liver (LIV), gall bladder (GBD), brown adipose tissue (BAT), kidney (KDN), heart (HEA) and muscle (MUS), from wild-type (WT) and Per1-/-/Per2-/- (DKO) mice housed under constant darkness and ad lib...
ORGANISM(S): Mus Musculus 
2023-11-28 | PXD047352 |
ProteomicsPCT2G_15min_HCC_25patients_115_files
PCT2G_15min_HCC_SCIEX6600_115_files_gaohuanhuan_20191112
ORGANISM(S): Homo Sapiens 
2020-07-14 | PXD020348 |
ProteomicsAccelerated Lysis and Proteolytic Digestion of Biopsy-level Fresh Frozen and FFPE Tissue Samples Using Pressure Cycling Technology
We developed an accelerated PCT method with doubled throughput while maintaining digestion efficiency, the number of proteins/peptides identified, as well as reproducibility of protein quantitation, compared to the previously reported method. The accelerated PCT method does not require new chemical ...
ORGANISM(S): Homo Sapiens 
2020-07-16 | PXD020353 |
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