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MetabolomicsMetabolomic Profiling of the Striatum in Shank3 Knockout ASD Rats: Effects of Early Swimming Regulation

OBJECTIVE: This study aimed to investigate the regulatory impact of early swimming intervention on striatal metabolism in Shank3 gene knockout ASD model rats.

METHODS: Shank3 gene knockout exon 11-21 male 8-day-old SD rats were used as experimental subject...

2024-09-27 | MTBLS8577 | MetaboLights
ProteomicsProteomic analysis of the aggregated proteins in cerebral vessles from MYPT1SMKO mice
To comprehensively understand the mechanism by which MYPT1 modulates the phenotypic switching of VSMCs after ischemic stroke, the proteins of cortical small vessel from MYPT1SMKO and WT mice subjected to MCAO or sham group were collected for proteomic screening.
ORGANISM(S): Mus musculus (Mouse) 
2021-08-21 | PXD027869 | Pride
Mypt1 Ischemmic stroke Vsmc Bbb 
ProteomicsQuantitative analysis of acetylation in Vero cells infected with Peste des petits ruminants virus
Peste des petits ruminants virus (PPRV) is a negative-stranded RNA virus belonging to the Paramyxoviridae family and causes acute, highly contagious disease in small ruminants. Lysine acetylation plays central role in regulating gene expression. However, the extent and function of lysine acetylation...
ORGANISM(S): Chlorocebus sabaeus 
2023-10-24 | PXD025081 | Pride
Post-translational modification lysine acetylation  protein-protein interaction peste des petits ruminants virus 
ProteomicsMouse lung proteomics and S-nitrosoproteomics using LC-MS/MS
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by excessive extracellular matrix deposition and impaired tissue repair. S-nitrosoglutathione reductase (GSNOR, encoded by ADH5) is a key enzyme that regulates protein S-nitrosylation by metabolizing S-nitrosoglutathione...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD061250 | Pride
Mouse Lung Lc-ms/ms 
ProteomicsSystematic Analysis of Lysine Succinylation in Vero cell infected with small ruminant morbillivirus
Small ruminant morbillivirus (SRMV), formerly named Peste-des-petits ruminanats virus (PPRV), belongs to the genus Morbillivirus genus in the family Paramyxoviridae and leads to a highly contagious disease in small ruminants, especially goats and sheep. Lysine succinylation is a newly identified and...
ORGANISM(S): Chlorocebus sabaeus 
2025-05-06 | PXD025025 | Pride
Post-translational modification  lysine succinylation  protein-protein interaction  small ruminant morbillivirus 
ProteomicsThe proteomics analysis of Crassostrea gigas under Zn and Cd contamination
Understanding organisms’ environmental adaptation mechanisms is a fundamental question in ecology and evolution. The oyster Crassostrea gigas is able to accumulate high levels of zinc (Zn) and cadmium (Cd) without self-poisoning, and is thus widely used for pollution detection. However, the molecula...
ORGANISM(S): Crassostrea gigas (Pacific oyster) (Crassostrea angulata) 
2018-10-25 | PXD003290 | Pride
Proteomics Crassostrea Ecotoxicology Heavy-metal 
ProteomicsInfluence of polysaccharides from Polygonatum kingianum on short-chain fatty acid production and quorum sensing in Lactobacillus faecis
Set the bacteria solution without polysaccharides from Polygonatum kingianum(PS) as the control group (CON group), and the bacteria solution with PS added as the administration group (PS group), the target strain treated with and without PS (20 μg/mL) was used for proteomic analysis.
ORGANISM(S): Lactobacillus sp. Y10 
2022-02-16 | PXD029210 | Pride
Lactobacillus faecis 
ProteomicsHuman cholangiocarcinoma LC-MS/MS
The glycosylation landscape of Human cholangiocarcinoma (CCA), and how it affects CCA diagnosis and prognosis, has recently emerged as an appealing research field.In this study, we used chemical glycoproteomic analysis Click-iG for systematic profiling of intact glycopeptides in CCA and HIBEpiC cell...
ORGANISM(S): Homo sapiens (Human) 
2024-06-22 | PXD048188 | Pride
Glycoproteomics Click-ig Cholangiocarcinoma 
TranscriptomicsTranscription profiling of human tetracycline-regulated cell line expressing an NF-kB inhibitor to systematically identify NF-kB dependent genes
TNF time course series of HelA tet off cells cultured in presence or absence of Dox; TNF is a pro-inflammatory cytokine that controls expression of inflammatory genetic networks. Although the Nuclear Factor-kB (NF-kB) pathway is crucial for mediating cellular TNF responses, the complete spectrum of...
ORGANISM(S): Homo sapiens 
2007-09-07 | E-GEOD-2624 | biostudies-arrayexpress
Proteomicspseudomonas fluorescens LC-MSMS
our work revealed a rewired regulatory network of mqsA in P. fluoresces, in which a new transcription factor is recruited and incorporated to fulfill the similar physiological function.
ORGANISM(S): Pseudomonas fluorescens F113 
2019-01-30 | PXD008578 | Pride
Pseudomonas fluorescens lc-msms proteomics 
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