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ProteomicsThe role of DENND10 in neuronal development
Neuron development requires an elaborate network of endosomal transport pathways, defects in which underlie multiple neurological diseases. DENND10/FAM45A is an ancient protein that is important for endosomal homeostasis. However, the role of DENND10 in the nervous system remained unknown. Here, we ...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-06 | PXD038623 | Pride
Neuron Neurite outgrowth Dennd10 Cad 
ProteomicsThe role of endosomal protein DENND10/FAM45A in extracellular vesicle release and cancer cell migration
Cell migration is key to tumor metastasis, the most challenging clinical problem in cancer treatment. Here we are investigating the role of DENND10/FAM45A, a recently described endosomal protein, in cancer cell migration via modulating the release of extracellular vesicles (EVs). Bioinformatics data...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-14 | PXD038264 | Pride
Extracellular vesicle Mouse Dennd10 Mammary cancer 4t1 
UnknownEVI1 promotes epithelial-to-mesenchymal transition, cancer stem cell features and chemo-/radioresistance in nasopharyngeal carcinoma.
Not available
S-EPMC6377731 | biostudies-literature
ProteomicsMetabolic Glycan Labelling or not (MGL/non-MGL) A375 cell derived extracellular vesicles (EVs) Proteomics data file for comparing the difference of EV proteins before and after MGL
This project including the results of protein identification file and six samples’ Raw file that were non-processed
ORGANISM(S): Homo sapiens (Human) 
2023-10-04 | PXD045742 | Pride
Evs Proteomics 
UnknownIGF2BP2 Drives Thyroid Cancer Dedifferentiation Through m6A-Dependent STAT1 mRNA Destabilization.
Not available
S-EPMC12780945 | biostudies-literature
UnknownAstaxanthin protects against early acute kidney injury in severely burned rats by inactivating the TLR4/MyD88/NF-κB axis and upregulating heme oxygenase-1.
Not available
S-EPMC7988001 | biostudies-literature
UnknownUltrasound-assisted deep eutectic solvent extraction of polysaccharides from Cercis chinensis bark: Optimization, kinetics and antioxidant activities.
Not available
S-EPMC12418997 | biostudies-literature
ProteomicsLC-MS/MS identification of XPO7-interacting proteins
Identification XPO7-interating proteins by ectopically expressed FLAG-tagged XPO7 proteins in HEK293T cells and performed coimmunoprecipitation (co-IP) with FLAG antibody followed by mass spectrometry analysis.
ORGANISM(S): Homo Sapiens 
2022-11-03 | PXD037890 |
UnknownAcetylation of TIR domains in the TLR4-Mal-MyD88 complex regulates immune responses in sepsis
Not available
S-SCDT-10_1038-S44318-024-00237-8 | biostudies-other
MetabolomicsAberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

OBJECTIVE: Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise relationships between the intestinal microbiome composition, uraemic toxins and rena...

2020-10-20 | MTBLS700 | MetaboLights
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