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ProteomicsProtein sequencing of human bone tissue at different ages
Bone is a dynamic organ in which bone formation mediated by osteoblasts balances against bone resorption mediated by osteoclasts to maintain bone homeostasis. With age, this balance gradually tilts toward bone resorption, leading to bone loss and osteoporosis. At the present study, the bone specimen...
ORGANISM(S): Homo sapiens (Human) 
2023-02-01 | PXD039538 | Pride
Bone Osteoporosis Human Proteome Aging 
UnknownAndrographolide Suppresses the Growth and Metastasis of Luminal-Like Breast Cancer by Inhibiting the NF-κB/miR-21-5p/PDCD4 Signaling Pathway.
Not available
S-EPMC8261247 | biostudies-literature
MetabolomicsAlterations of fecal microbiota and plasma metabolome in patients with Parkinson's disease with rapid eye movement sleep disorder

Objectives: Patients with Parkinson's disease (PD) with probable Rapid eye movement sleep Behavior Disorder (RBD) (PD-RBD), a specific subtype of PD, is characterized by the presence of more severe motor and non-motor symptoms. This study aimed to elucidate the characteristics and interactions of...

2025-05-07 | MTBLS11094 | MetaboLights
ProteomicsIsolation and Comprehensive Analysis of Cochlear Tissue-derived Small Extracellular Vesicles
Label-free quantitative proteomics analysis of CDsEVs, with the same amount of protein of cochlear tissues used as the control
ORGANISM(S): Mus Musculus 
PXD056591 |
ProteomicsProteomics and bioinformatics analysis of Fasciola hepatica somatic proteome in different growth phases
In this study, high-performance liquid chromatography-tandem mass spectrometry was conducted to analyze the differences in the expression of F. hepatica
ORGANISM(S): Fasciola Hepatica 
2020-04-25 | PXD018798 |
ProteomicsMetabolic-engineered probiotic- OMVs as nanovaccine mediating sequential immunomodulation for chronic bone infection immunotherapy
Lei et al. screen out Lactococcus lactis OMVs (Lac-OMVs) and develop metabolic-engineered NAD+-Lac-OMVs nanovaccine with potent tissue repair therapeutic effect. NAD+-Lac-OMVs sequentially activate dendritic cells by membrane component and reprogram inflammatory macrophages for anti-inflammation and...
ORGANISM(S): Mus Musculus 
2026-03-23 | PXD076052 |
ProteomicsProteomic and Acetylome Alterations in Obesity-related Osteoarthritic Mouse Cartilage
Male mice aged 4 weeks were housed under controlled conditions and assigned to either a normal diet or a high-fat diet for 16 weeks to establish an obesity model. At 12 weeks, osteoarthritis was induced using the destabilization of the medial meniscus procedure under anesthesia, while sham-operated ...
ORGANISM(S): Mus Musculus 
PXD062707 |
Proteomicsinteractome and proteomic survey of PMBCs from COVID-19 patients
Virus-host interactome and proteomic survey of PMBCs from COVID-19 patients reveal potential virulence factors influencing SARS-CoV-2 pathogenesis
ORGANISM(S): Homo Sapiens 
2020-06-28 | PXD020067 |
ProteomicsReconstitution of Pluripotency from Mouse Fibroblast through Sall4 Overexpression
We report that SALL4 alone, under an optimized reprogramming medium iCD4, is capable of reprogramming mouse fibroblasts into iPSCs. To identify SALL4-direct-interacting proteins, we performed immunoprecipitation followed by mass spectrometry (IP-MS) using MEFs overexpressing WT-SALL4 or SALL4 mutan...
ORGANISM(S): Mus Musculus 
2024-11-05 | PXD057516 |
ProteomicsTargeting tRNA-dependent tyrosine usage unveils a metabolic vulnerability in hepatocellular carcinoma
proteomics and metabolomics analysis of HCC cells cultured in tyrosine deprived medium
ORGANISM(S): Homo Sapiens 
2025-12-30 | PXD072551 |
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