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ProteomicsS-nitrosocysteine proteomics of Schistosoma japonicum collected from infected mice and rats
Rats and mice were infected with Schistosoma japonicum, and the worms were collected from infected rats and mice. Worms in rats were exposed to high level of NO, while the worms in mice were not. Then a S-nitrosocysteine proteomics of Schistosoma japonicum collected from infected rats and mice was p...
ORGANISM(S): Schistosoma Japonicum 
PXD041667 |
MetabolomicsDistinct metabolic profiling is correlated with bisexual flowers formation resulting from exogenous ethephon induction in melon (Cucumis melo L.)

Melon (Cucumis melo L.) is an agronomically important vegetable. Most cultivars of melon are andromonoecious and bisexual flowers only emerged from the leaf axil of lateral branches. However, the regulatory mechanism contributing to the occurrence of bisexual flowers were still obscure. ...

2022-03-10 | MTBLS2993 | MetaboLights
MetabolomicsAge-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.

The incidence of intestinal diseases increases with age, but the regulators of gut aging and the molecules linking gut aging and diseases remain largely unknown. By profiling the transcriptome, proteome, phosphoproteome and metabolome of 104 Macaca fascicularis large intestinal tissues, ...

2023-12-14 | MTBLS7612 | MetaboLights
MetabolomicsThe effects of different rootstocks on aroma components, activities and genes expression of aroma-related enzymes in oriental melon fruit

Grafting is widely applied in the cultivation of melon. In this study, 'Qinmi No.1' [Cucumis melo L. (QG)] and 'Ribenxuesong' [Cucurbita maxima Duch. (RG)] were used as rootstocks for 'QingxinYangjiaocui' (Cucumis melo L.). The results showed that grafting with...

2023-11-21 | MTBLS8677 | MetaboLights
Proteomicslabel free quantitative proteomics for determining the biological characterastic of eukaryocyte with or without BHB.
BHB is the major part of ketone body in plasm that is usually at low concentration. Dramatical increase of BHB is due to prologation fasting or diabetes. In addation to enegetic carrier for metabolic reprogramming, BHB is also involved in epigenetic regulation. Here, we illustrats the BHB-induced pr...
ORGANISM(S): Homo sapiens (Human) 
2025-07-04 | PXD051685 | Pride
Human Bhb Label-free Lc-ms/ms 
ProteomicsLabel-free DDA proteome for identifying the interacting proteins of HBO1
HBO1 is an important transcriptional activator for organism to respond to natural stress. Here, we performed IP-MS for determining the interacting proteins of HBO1 under stimulation of BHB.
ORGANISM(S): Homo sapiens (Human) 
2025-07-04 | PXD051692 | Pride
Human Label-free Ip-ms Hbo1 
ProteomicsSILAC based quantitative 3-hydroxybutyromics of HBO1-WT and HBO1-KO HeLa cells
Ketogenesis derived BHB facilitates 3-hydroxybutyrylation on lysine linking metabolism with epigenetic regulation. Herein, we found HBO1 served as 3-hydroxybutyryltransferase preferentially catalyzing lysine 9 of histone H3 (H3K9bhb). Moreover, total 1171 Kbhb sites on 582 proteins were identified. ...
ORGANISM(S): Homo sapiens (Human) 
2025-07-04 | PXD051668 | Pride
Human Cervical cancer Kbhb Hbo1 Lc-ms/ms 
ProteomicsIntegrative proteomics and precision N-glycoproteomics analyses of rheumatoid arthritis synovia reveal immune-associated glycopeptides
The precision glycoproteome in the synovium and its clinical significance are completely unknown. We performed precision N-glycoproteomics analysis of RA and OA synovial tissues, and identified many immune-associated N-glycopetides in this study for the first time, providing new insights into the me...
ORGANISM(S): Homo Sapiens 
2023-03-10 | PXD037581 |
ProteomicsProteomic sequencing of atrial fibrosis rat model caused by chronic intermittent hypoxia
This study was aimed to understand the changes of proteins occurring in atrial tissue of atrial fibrillation (AF) rat model based on proteome sequencing.SD rats were used for AF model construction by chronic intermittent hypoxia (CIH) induction. The tissue pathological changes were observed by hemat...
ORGANISM(S): Rattus Norvegicus 
PXD042312 |
ProteomicsEasySCP Unveils Extensive Liver Zonation at Single-cell Proteomics Resolution
The widespread adoption of single-cell proteomics (SCP) in biology has been limited by complex workflows and reliance on specialized instrumentation. Here we present EasySCP, a high-throughput and lossless method that integrates FACS-based single-cell sorting, an all-in-one, single-step digestion pr...
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-10-30 | PXD070083 |
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