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UnknownComprehensive analysis identifies cuproptosis-related gene DLAT as a potential prognostic and immunological biomarker in pancreatic adenocarcinoma.
Not available
S-EPMC10276918 | biostudies-literature
UnknownMeaningful nomograms based on systemic immune inflammation index predicted survival in metastatic pancreatic cancer patients receiving chemotherapy
Not available
S-EPMC11236459 | biostudies-literature
ProteomicsThe METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates metabolism and development via translation (Identification of m1A mRNA methyltransferase in nucleus by TMT11-LC-MS/MS)
m1A has long been known to be important in tRNA and rRNA, but we recently mapped many m1A sites in mRNA as well. m1A is found on the 5’ ends of genes, usually around the first splice site, but we have yet to understand how it effects transcript fate. Identifying the methyltransferase would be a ma...
ORGANISM(S): Homo sapiens (Human) 
2021-11-30 | PXD028832 | Pride
Mettl5 Mass spectrometry Proteomics M1a mrna methyltransferase Trmt112 
ProteomicsLRRK2-RAB12 Complex Suppresses Primary Ciliogenesis and Regulates Centrosome Homeostasis in Astrocytes
Leucine-rich repeat kinase 2 (LRRK2) phosphorylates a subset of RAB GTPases and this phosphorylation is elevated by Parkinson’s disease (PD)-linked mutations of LRRK2. However, the precise function of the specific RAB GTPase targeted by LRRK2 signaling remains to be elucidated. Here we solve the str...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-18 | PXD048732 | Pride
Structure of lrrk2-rab12 protein complex Proteomics Lrrk2 Ciliogenesis Centrosome homeostasis Parkinson’s disease Tandem mass tag 
UnknownMicroplastic abundance in placental chorionic villi detected by pyrolysis-gas chromatography/mass spectrometry in cases of spontaneous miscarriage during early pregnancy.
Not available
S-EPMC12478273 | biostudies-literature
TranscriptomicsRegulatory role of SrrAB two-component system in Staphylococcus epidermidis growth and biofilm formation
Biofilm formation is considered the most important factor involved in pathogenicity of Staphylococcus epidermidis.We investigated the role of two-component signal transduction system (TCS) srrAB, which was up-regulated under micro-aerobic condition, in the growth and biofilm formation of S. epidermi...
ORGANISM(S): Staphylococcus epidermidis 
2014-11-21 | E-GEOD-47101 | biostudies-arrayexpress
ProteomicsMass spectrometry analysis of proteins interacting with cGAS
o identify the potential associated proteins of cGAS, we performed co-IP followed by mass spectrometry analysis in HEK293A cells stably expressing SFB-tagged cGAS.
ORGANISM(S): Homo sapiens (Human) 
2022-02-07 | PXD023597 | Pride
Lc-ms/ms Hek293a Cgas 
GenomicsIgA Nephropathy GWAS (IGANGWAS)

We report a genome-wide association study of IgA nephropathy, a main cause of kidney failure. All subjects were of Chinese Han ancestry, of which 1,194 were cases and 902 controls. Genomic DNA samples extracted from whole blood were genotyped on the Illumina 610 Quad platform.

phs000431.v1.p1 | EGA
UnknownFusobacterium nucleatum upregulates MMP7 to promote metastasis-related characteristics of colorectal cancer cell via activating MAPK(JNK)-AP1 axis.
Not available
S-EPMC10561506 | biostudies-literature
TranscriptomicsComparison of gene expression profiles in cultivated peanut (Arachis hypogaea L.) under strong artificial selection
Comparison of gene expression profiles of widespread peanut cultivars for exploring the expression data in pod and leaf with regard to signatures of artificial selection We investigated the overall expression by hybridizing the microarray (GPL13178) with RNA samples from pods and leaves of five se...
ORGANISM(S): Arachis hypogaea 
2012-06-18 | E-GEOD-30128 | biostudies-arrayexpress
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