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ProteomicsGlobal quantification of glutathione S-transferases in human serum using LC-MS/MS coupled with affinity enrichment
The concentrations of glutathione S-transferases (GSTs) in serum are considered disease biomarkers. Members of the GST superfamily often exhibit functional overlap, and can compensate for each other. Global and quantitative evaluation of serum GSTs is therefore urgent, but we currently lack an effic...
ORGANISM(S): Homo Sapiens 
2022-01-19 | PXD031061 |
UnknownDetailed Structural Analysis of the Immunoregulatory Polysaccharides from the Mycobacterium Bovis BCG.
Not available
S-EPMC9458083 | biostudies-literature
ProteomicsQuantitative analysis to the subcellular proteome in response to cathepsin D knockdown in HeLa cells
Cathepsin D is reportedly to be closely associated with tumor development, migration and invasion, but its pathological mechanism is not fully elucidated. We aimed to evaluate phenotypic changes and molecular events in response to cathepsin D knockdown. Lowering endogenous cathepsin D abundance (CR)...
ORGANISM(S): Homo sapiens (Human) 
2015-12-17 | PXD002844 | Pride
Cytosol Lysosome Silac Nucleus Subcellular fractionation 
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
MetabolomicsLipidomics profiling reveals the role of glycerophospholipid metabolism in psoriasis
Psoriasis is a common and chronic inflammatory skin disease complicated by genetic-environmental interactions. Although genomic, transcriptomic and proteomic analyses have been performed to investigate the pathogenesis of psoriasis, the role of metabolites in psoriasis, particularly of lipids, remai...
2017-08-22 | MTBLS408 | MetaboLights
ProteomicsEnrichment strategy for searching missing protein
Enrichment strategy for searching missing protein is a project under the guidance of Chromosome-Centric Human Proteome Project (C-HPP). We developed systematical enrichment strategies for revealing the existence of MPs including low molecular weight (LMW), membrane proteins, post-translational modif...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-12 | MSV000083957 | MassIVE
ProteomicsTargeting NADPH oxidase and integrin α5β1 to inhibit neutrophil extracellular traps-mediated metastasis in colorectal cancer
Using multiple mass spectrometry-based proteomic approaches, our results comprehensively elucidate the entire process by which increased NETs accelerate tumor progression.
ORGANISM(S): Homo Sapiens 
2023-10-27 | PXD046490 |
ProteomicsIsobaric tags for relative and absolute quantification based on quantitative proteomic analysis on inhibitor of apoptosis protein-like protein-2 knocked-down MCF-7 breast cancer cells
Although the inhibitor of apoptosis protein-like protein-2 (ILP-2) is regarded as a novel growth enhancer for breast cancer, its mechanism on breast cancer cell growth remains elusive and requires further study. In this study, isobaric tags were applied for relative and absolute quantification (iTRA...
ORGANISM(S): Homo Sapiens 
2019-02-25 | PXD012848 |
Proteomics[HPP-2.0]A simple, rapid, and practical method for single-cell proteomics based on mass-adaptive coating of synthetic peptides
Here, we report a simple, rapid, and practical approach of mass-adaptive coating-assisted single-cell proteomics (Mad-CASP). Combined with the designed synthetic peptides and novel data acquisition strategy, 1240 ± 93 (n = 3) proteins were identified from a single HeLa cell by Mad-CASP.
ORGANISM(S): Homo Sapiens 
2023-10-17 | PXD046177 |
ProteomicsHs_C-HPP_EnrichmentStrategy_membrane
Enrichment strategy for searching missing protein, HCCLM6 and MHCC97L, membrane and
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005437 | PeptideAtlas
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