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ProteomicsZNF524 directly interacts with telomeric DNA and supports telomere integrity
Telomeres are nucleoprotein structures at the ends of linear chromosomes. In humans, they consist of TTAGGG repeats, which are bound by dedicated proteins such as the shelterin complex. This complex blocks unwanted DNA damage repair at telomeres, e.g. by suppressing non-homologous end joining (NHEJ)...
ORGANISM(S): Homo sapiens (Human) 
2023-10-21 | PXD043084 | Pride
Trf2 Genome integrity Alt Telomeres Rap1 Znf524 Osteosarcoma 
ProteomicsZNF524 directly binds telomeres and supports their integrity via TRF2/RAP1
Telomeres are nucleoprotein structures at the ends of linear chromosomes. In humans, they consist of TTAGGG repeats, which are bound by dedicated proteins such as the shelterin complex. This complex consists of six proteins (TRF1, TRF2, RAP1, POT1, TPP1 and TIN2) and blocks unwanted DNA damage repai...
ORGANISM(S): Homo sapiens (Human) 
2023-10-21 | PXD024630 | Pride
Genome stability Telomeres Znf524 Bioid 
GenomicsZNF524 directly binds telomeres and supports their integrity via TRF2/RAP1
ZNF524 directly binds telomeres and supports their integrity via TRF2/RAP1
PRJNA806777 | ENA
UnknownZNF524 directly interacts with telomeric DNA and supports telomere integrity.
Not available
S-EPMC10716145 | biostudies-literature
GenomicsZNF524 directly binds telomeres and supports their integrity via TRF2/RAP1
Telomeres are nucleoprotein structures at the ends of linear chromosomes. In humans, they consist of TTAGGG repeats, which are bound by dedicated proteins such as the shelterin complex. This complex blocks unwanted DNA damage repair at telomeres, e.g. by suppressing non-homologous end joining (NHEJ)...
ORGANISM(S): Homo sapiens 
2023-10-23 | GSE196661 | GEO
ProteomicsZNF524 directly binds telomeres and supports their integrity via TRF2/RAP1
Telomeres are nucleoprotein structures at the ends of linear chromosomes. In humans, they consist of TTAGGG repeats, which are bound by dedicated proteins such as the shelterin complex. This complex consists of six proteins (TRF1, TRF2, RAP1, POT1, TPP1 and TIN2) and blocks unwanted DNA damage repai...
ORGANISM(S): Homo sapiens (Human) 
2023-10-22 | PXD031416 | Pride
Lc-ms/ms 
Genomics
mRNA sequencing of ZNF524 KO in H. sapiens U2OS cells
PRJNA804430 | ENA
GenomicsChIP-seq from HEK293 (ENCSR418NZA)
eGFP-ZNF524 ChIP-seq on human HEK293 cells. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2017-10-23 | GSE105505 | GEO
UnknownEvaluating the biological functions of the prognostic genes identified by the Pathology Atlas in bladder cancer.
Not available
S-EPMC7709834 | biostudies-literature
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