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TranscriptomicsTranscription profiling by array of human HepG2 cells treated with TCDD
The integration of different M-^SomicsM-^T technologies has already been shown in several in vivo studies to offer a complementary insight into cellular responses of toxic processes. We therefore hypothesize that the combining of transcriptomics and metabonomics data may improve the understanding of...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-MEXP-2817 | biostudies-arrayexpress
TranscriptomicsCombined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial
The obese, insulin resistant state is characterized by impairments in lipid metabolism. Dietary polyphenols might improve these deteriorations. We have previously shown that 3-days supplementation of combined Epigallocatechin-gallate and Resveratrol (E+R) increased energy expenditure, which was acco...
ORGANISM(S): Homo sapiens 
2016-08-03 | E-GEOD-71614 | biostudies-arrayexpress
UnknownAccurately Predicting Protein pKa Values Using Nonequilibrium Alchemy.
Not available
S-EPMC10653114 | biostudies-literature
TranscriptomicsEffects of a diet high in monounsaturated fat and a full Mediterranean diet on PBMC whole genome gene expression and plasma proteins
This study aimed to identify the effects of replacement of saturated fat (SFA) by monunsaturated fat (MUFA) in a western-type diet and the effects of a full Mediterranean (MED) diet on whole genome PBMC gene expression and plasma protein profiles. Abdominally overweight subjects were randomized to a...
ORGANISM(S): Homo sapiens 
2012-08-02 | E-GEOD-30509 | biostudies-arrayexpress
TranscriptomicsProfiling of promoter occupancy by PPARM-NM-1 in human hepatoma cells via ChIP-chip analysis
The transcription factor Peroxisome Proliferator-Activated Receptor M-NM-1 (PPARM-NM-1) is an important regulator of hepatic lipid metabolism. While PPARM-NM-1 is known to activate transcription of numerous genes, no comprehensive picture of PPARM-NM-1 binding to endogenous genes has yet been report...
ORGANISM(S): Homo sapiens 
2010-11-23 | E-GEOD-25547 | biostudies-arrayexpress
TranscriptomicsHoxd genes and fiber type-specific markers specify adult mouse muscle type in a diet-independent way
Introduction: The mouse skeletal muscle is composed of four distinct fiber types that differ in contractile function, number of mitochondria and metabolism. Every muscle group has a specific composition and distribution of the four fiber types. Until now, three genes (CnA, PGC1α and PPARδ) are ident...
ORGANISM(S): Mus musculus 
2010-09-03 | E-GEOD-18127 | biostudies-arrayexpress
ProteomicsMS-based identification of AcP10 interaction partners.
In times of cellular stress, such as during virus infections, the integrated stress response (ISR) blocks translation initiation through phosphorylation of the essential translation initiation factor eIF2. Phosphorylated eIF2 (p-eIF2) sequesters the eIF2-specific guanidine exchange factor (GEF) eIF2...
ORGANISM(S): Homo sapiens (Human) 
2020-07-24 | PXD011879 | Pride
Ap-ms Eif2 Bw10 Interactome Eif2b 
TranscriptomicsA saturated fatty acid rich diet can induce an 'obese-like' gene expression profile in adipose tissue
We investigated the effect of a saturated (SFA) and a monounsaturated (MUFA) rich diet on insulin sensitivity and adipose tissue gene expression profiles of subjects at risk for metabolic syndrome. A controlled-feeding trial was performed with 20 moderately overweight subjects. Subjects received a S...
ORGANISM(S): Homo sapiens 
2010-02-13 | E-GEOD-14954 | biostudies-arrayexpress
no omics definedTranscription profiling of mouse fibroblast-like cells infected with mouse hepatitis virus
Effect of mouse hepatitis virus strain A59 replication on gene expression and mRNA stability in LR cells
ORGANISM(S): Mus musculus 
2007-11-13 | E-MEXP-895 | biostudies-arrayexpress
TranscriptomicsA high fat diet causes obesity and insulin resistance in mice, but induces small changes in the muscle transcriptome
An 8-week high fat palm oil diet causes obesity and insulin resistance in C57BL/6J mice, but induces only small changes in the muscle transcriptome. Introduction: The metabolic syndrome (MS) is a cluster of metabolic abnormalities linked to an increased risk of type 2 diabetes and cardiovascular dis...
ORGANISM(S): Mus musculus 
2010-08-10 | E-GEOD-17576 | biostudies-arrayexpress
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