Genetic evidence strengthens the bidirectional connection between gut microbiota and Shigella infection: insights from a two-sample Mendelian randomization study.
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ABSTRACT:
SUBMITTER: Peng J
PROVIDER: S-EPMC10941758 | biostudies-literature | 2024
REPOSITORIES: biostudies-literature
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Genetic evidence strengthens the bidirectional connection between gut microbiota and <i>Shigella</i> infection: insights from a two-sample Mendelian randomization study.
Peng Jingyi J Cai Kun K Chen Guanglei G Liu Linxiao L Peng Lili L
Frontiers in microbiology 20240301
<h4>Background</h4>In recent investigations, substantial strides have been made in the precise modulation of the gut microbiota to prevent and treat a myriad of diseases. Simultaneously, the pressing issue of widespread antibiotic resistance and multidrug resistance resulting from <i>Shigella</i> infections demands urgent attention. Several studies suggest that the antagonistic influence of the gut microbiota could serve as a novel avenue for impeding the colonization of pathogenic microorganism ...[more]
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