Fast in vivo ²³ Na imaging and T2∗ mapping using accelerated 2D-FID UTE magnetic resonance spectroscopic imaging at 3 T: Proof of concept and reliability study.

ABSTRACT:

Purpose

To implement an accelerated MR-acquisition method allowing to map T2∗ relaxation and absolute concentration of sodium within skeletal muscles at 3T.

Methods

A fast-UTE-2D density-weighted concentric-ring-trajectory ²³ Na-MRSI technique was used to acquire 64 time points of FID with a spectral bandwidth of 312.5 Hz with an in-plane resolution of 2.5 × 2.5 mm² in ~15 min. The fast-relaxing ²³ Na signal was localized with a single-shot, inversion-recovery-based, non-echo (SIRENE) outer volume suppression (OVS) method. The sequence was verified using simulation and phantom studies before implementing it in human calf muscles. To evaluate the 2D-SIRENE-MRSI (UTE = 0.55 ms) imaging performance, it was compared to a 3D-MRI (UTE = 0.3 ms) seq

SUBMITTER: Alhulail AA 

PROVIDER: S-EPMC7832172 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature