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GenomicsHemolysis-induced hepatic ferroptosis following xenotransfusion of genetically modified pig red blood cells
Hemolysis-induced hepatic ferroptosis following xenotransfusion of genetically modified pig red blood cells
PRJNA1311028 | ENA
TranscriptomicsHemolysis-induced hepatic ferroptosis following xenotransfusion of genetically modified pig red blood cells
Following a worsening blood supply shortage, researchers are investigating the application of genetically modified pig blood for human transfusion. To overcome cross-species immunological barriers, researchers utilize gene editing to remove the expression of three major carbohydrate xenoantigens (α-...
ORGANISM(S): Macaca fascicularis 
2025-12-30 | GSE306520 | GEO
UnknownCompensation of Disabled Organogeneses in Genetically Modified Pig Fetuses by Blastocyst Complementation.
Not available
S-EPMC6962638 | biostudies-literature
UnknownXenotransplantation of Genetically Modified Neonatal Pig Islets Cures Diabetes in Baboons.
Not available
S-EPMC9243461 | biostudies-literature
ProteomicsA scalable, clinically severe pig model for Duchenne muscular dystrophy
Large animal models for Duchenne muscular dystrophy (DMD) are indispensible for preclinical evaluation of novel diagnostic procedures and treatment strategies. To evaluate functional consequences of Duchenne muscular dystrophy (DMD) in skeletal muscle and myocardium, we used a new genetically engine...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-12-01 | PXD027772 | Pride
Proteomics Dmd Duchenne muscular dystrophy Pig Animal model 
UnknownHemolysis-induced hepatic ferroptosis following xenotransfusion of genetically modified pig red blood cells.
Not available
S-EPMC12711946 | biostudies-literature
UnknownComplement Activation and Hemolysis in Non-human Primates Following Transfusion of Genetically Modified Pig Red Blood Cells.
Not available
S-EPMC12370810 | biostudies-literature
ProteomicsProteomic analysis of adipose tissue from a pig model of mutant INS gene induced diabetes of youth (MIDY)
To evaluate functional consequences of insulin-deficient diabetes mellitus for adipose tissue, we used a genetically engineered pig model of mutant INS gene induced diabetes of youth (MIDY). Adipose tissue samples of MIDY pigs and wild-type (WT) littermate controls were analyzed by label-free proteo...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-02-17 | PXD026910 | Pride
Animal model Biobank Adipose tissue Midy Pig model Diabetes Lc-ms/ms 
UnknownPig-to-human kidney xenotransplants using genetically modified minipigs.
Not available
S-EPMC11513830 | biostudies-literature
UnknownSomatic cell reprogramming-free generation of genetically modified pigs.
Not available
S-EPMC5023319 | biostudies-literature
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