heterodimer - OmicsDI

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UNIPROT ID/AC

P17676 (2)
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ENSG00000204531 (2)

CHEBI ID

CHEBI:16480 (1)
CHEBI:36080 (1)
CHEBI:33699 (1)

Metabolite Name

12-KetoLCA (1)
UCA (1)
IsoDCA (1)
N-Acetyalanine (1)
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N-Acetytyrosine (1)
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N-Acetyaspartic acid (1)
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10Z-Nonadecenoic acid (1)
Ribose 5-phosphate (1)
5-Hydroxy-tryptophan (1)
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1H-Indole-3-acetamide (1)
DHA (1)

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Modelling Approach

Ordinary differential equation model (15)

Lab affiliation

Gene Center Munich and Department of Biochemistry, Ludwig-Maximilians-Universität München, Feodor-Lynen-Str. 25, 81377 Munich, Germany (2)
King's College London, Chemistry Department, 7 Trinity Street, London, SE1 1DB, UK (2)
1. INSERM U1287, Université Paris-Saclay, Gustave Roussy Cancer Center, Villejuif, France 2. Université Paris-Saclay, Faculté de Médecine, Le Kremlin-Bicêtre, France (1)
1. Laboratoire de Spectrométrie de Masse BioOrganique, IPHC UMR 7178, Université de Strasbourg, CNRS, 67000 Strasbourg, France 2. Infrastructure Nationale de Protéomique ProFI – FR2048, 67087 Strasbourg, France (1)
1Brunason Center for Translational Vision Research, Department of Ophthalmology and Visual Sciences, Gavin Herbert Eye Institute, University of California, Irvine, Irvine, CA, 92697, USA; 2Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, 92697, USA; 3Department of Chemistry, University of California, Irvine, Irvine, CA, 92697, USA; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, 92697, USA (1)
Andalusian Center for Molecular Biology and Regenerative medicine, CABIMER-US (1)
Baker Heart and Diabetes Institute, Aus (1)
Basic Immune System of Plants / Protein Mass Spectrometry Max Planck Institute for Plant Breeding Research Carl-von-Linne-Weg 10, 50829 Cologne, Germany (1)
Bio3/Bioinformatics and Molecular Genetics, University of Freiburg, 30Schänzlestrasse 1, D-79104 Freiburg, Germany (1)
Bioanalytical Mass Spectrometry, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany University Medical Center Göttingen, Institute of Clinical Chemistry, Bioanalytics Group, Göttingen, Germany Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, Germany (1)
Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, Scotland, United Kingdom (1)
CABIMER - University of Sevilla (1)
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Univeristy of Cambridge, UK (1)
Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC 3800, Australia. Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC 3800, Australia. (1)
Cell Biology and Physiology, Washington University in St. Louis, United States (1)
Cell and Chemical Biology Leiden University Medical Center Leiden, The Netherlands (1)
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Centre for Medical Genetics, Institute of Reproductive Genetics, University of Münster, Vesaliusweg 12-14, 48149 Münster, Germany. (1)
Centre for Medical Genetics, Institute of Reproductive Genetics, University of Münster, Vesaliusweg 12-14, 48149, Münster, Germany. (1)
Chronic Disease Programme (UFIEC), Instituto de Salud Carlos III, Madrid, Spain (1)
Department Pharmacology, Physiology and Neurosciences NJMS- RUTGERS (1)
Department of Biochemistry, University of Washington, Seattle, WA, USA (1)
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Department of Chemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK Kavli Institute for NanoScience Discovery, Dorothy Crowfoot Hodgkin Building, Oxford OX1 3QU, UK (1)
Department of Craniofacial Biology, University of Colorado Anschutz Medical Campus, United States of America (1)
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Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA (1)
Department of Molecular, Cellular and Developmental Biology. Yale University, 260 Whitney Ave, New Haven, CT. 06520, USA. (1)
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Transcription profiling of human rhabdomyosarcoma cells expressing Myod and E-protein heterodimer and controls

Rhabdomyosarcomas (RMS) are characterized by expression of myogenic specification genes, such as MyoD and/or Myf5, as well as their bHLH partners for heterodimerization, the E-proteins. We have shown that expression of a forced heterodimer of MyoD with one of the E2A proteins, E12, leads to differe...

ORGANISM(S): Homo sapiens

2009-02-21 | E-GEOD-14825 | biostudies-arrayexpress

PDGFRalpha/beta heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

The platelet-derived growth factor receptor (PDGFR) family of receptor tyrosine kinases consists of two receptors, PDGFRalpha and PDGFRbeta, that homodimerize and heterodimerize upon ligand binding. Here, we tested the hypothesis that differential internalization and trafficking dynamics of the vari...

ORGANISM(S): Homo sapiens (Human)

2025-04-25 | PXD048421 | Pride

Transcription profiling of mouse wild type adult male mouse livers vs transgenic mice expressing human Small Heterodimer Partner in hepatocytes

Comparison of gene expression in adult male mouse livers between wildtype mice and Transgenic mice expressing human Small Heterodimer Partner in hepatocytes.

ORGANISM(S): Mus musculus

2006-01-01 | E-MEXP-294 | biostudies-arrayexpress

The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury

PRJNA1074411 | ENA

Molecular determinant for MED1 interaction with the VDR-RXR heterodimer

To provide structural insights into the mechanism of the specific association of the coactivator MED1 with the Vitamin D nuclear (VDR)-RXR heterodimer, we used combined structural methods including X-ray crystallography, small angle X-ray scattering (SAXS), NMR, hydrogen-deuterium exchange coupled t...

ORGANISM(S): Homo sapiens (Human)

2021-02-10 | PXD019530 | Pride

Nuclear receptor Vdr-rxr Xl-ms Hdx-ms

BMAL1–HIF2A heterodimer modulates circadian variations of myocardial injury

PRJNA1082392 | ENA

Transcription profiling of small heterodimer partner deficiency (SHP) knockout mice heart

The small heterodimer partner (SHP) regulates fatty acid oxidation and lipogenesis in the liver by regulating peroxisome proliferator-activated receptor (PPAR) Î³ expression. SHP is also abundantly expressed in the myocardium. Therefore, we investigated the myocardial gene expression in a SHP deleti...

ORGANISM(S): Mus musculus

2017-12-01 | E-MTAB-5329 | biostudies-arrayexpress

PPARa-NFkB heterodimer mediates obesity cardiomyopathy through autocrine production of IL-6

PRJNA1402793 | ENA

A new obligate CXCL4–CXCL12 heterodimer for studying chemokine heterodimer activities and mechanisms

Not available

S-EPMC9561612 | biostudies-literature

Gene expression profile in the tethered Nrf1-MafG (T-N1G) heterodimer-expressing small Maf-deficient cells [RNA-seq]

PRJNA780313 | ENA

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