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ProteomicsIDENTIFICATION OF SUMO-2/3 MODIFIED PROTEINS ASSOCIATED WITH MITOTIC CHROMOSOMES
Sumoylation is essential for progression through mitosis, but the specific protein targets and functions remain poorly understood. In this study, we used chromosome spreads to more precisely define the localization of SUMO-2/3 to the inner-centromere and protein scaffold of mitotic chromosomes. We a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-10-07 | MSV000078890 | MassIVE
ProteomicsMitotic chromosome scaffold
Quantitative proteomics analysis of mitotic chromosome scaffold based on SILAC
ORGANISM(S): Gallus Gallus 
2018-10-07 | PXD007269 | JPOST Repository
ProteomicsMitotic chromatin proteomics - Proteomics analysis with a nano Random Forest approach reveals novel functional interactions regulated by SMC complexes on mitotic chromosomes
we used stable isotope labeling with amino acids in cell culture (SILAC) to compare the proteomes of mitotic chromosomes isolated from cell lines harboring conditional knockouts of members of the condensin (SMC2, CAP-H, CAP-D3), cohesin (Scc1/Rad21), and SMC5/6 (SMC5) complexes.
ORGANISM(S): Gallus gallus (Chicken) 
2016-05-31 | PXD003427 | Pride
Mitosis Smc Chromatin 
Proteomicsmitotic chromosome scaffold SMC2ON vs OFF
Quantitative proteomics analysis of mitotic chromosome scaffold based on SILAC
ORGANISM(S): Gallus Gallus 
2018-10-07 | PXD008429 | JPOST Repository
OtherIdentification of SUMO-2/3 modified proteins associated with mitotic chromosomes.
Data from Massive, ID: MSV000078890, PXD ID: PXD001534. File: MM_8A2_SUMO23_mitosis_C_75KDa_v1.mzml. Published as part of Proteomics. 2014 Nov 4 . From the Abstract: {{i}} ... In this study, we used chromosome spreads to more precisely define the localization of SUMO-2/3 to the inner-centromere and...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32310005148 | GPMDB
Resource Reanalysis 
ProteomicsLoss of H3K9 tri-methylation alters mitotic chromosome compaction and transcription factor retention during mitosis
Recent studies have shown that repressive chromatin machinery, including DNA methyltransferases (DNMTs) and Polycomb Repressor Complexes (PRCs), bind to chromosomes throughout mitosis and their depletion results in increased chromosome size. Enzymes that catalyse H3K9 methylation, such as Suv39h1, S...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-12 | PXD030771 | Pride
Chromatin  mitotic chromosomes  h3k9me3  suv39h1  suv39h2  ezh2  esrrb 
ProteomicsAnalysis of barley chromosomal proteome: a multiapproach exploration of flow cytometry-sorted mitotic chromosomes
Proteins contribute to the structure of chromatin and regulate its functions. The basic building block of chromatin in eukaryotes is the nucleosome containing histones. Structural maintenance of chromosomes complexes perform the assembly of genomic DNA into the higher organizational structures of in...
ORGANISM(S): Hordeum vulgare (Barley) 
2021-07-21 | PXD024689 | Pride
Prediction Proteomics Mass spectrometry Flow cytometry Barley Chromatin Chromosome 
ProteomicsAnalysis of factors bound to native metaphase ESC chromosomes following purification by flow cytometry
Stem cells are able to self-renew and also generate differentiated progeny. How gene expression patterns are transmitted through mitosis remains unresolved. Conventional studies have relied upon rigorous cell-cycle-stage synchronisation to find factors in mitotic lysates that could ‘bookmark’ the ge...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-15 | PXD015251 | Pride
Mitosis Stem cells Chromosomes Chromatin 
Proteomicsphosphoproteome in mitotic chromosomes
Identification and characterization of mitosis-specific phosphorylation in mitotic chromosome-associated proteins
ORGANISM(S): Gallus gallus (Chicken) 
2016-09-27 | PXD003877 | Pride
Mitosischromatin phosphorylation 
ProteomicsHbo1 and Msl complexes preserve differential compaction and H3K27me3 marking of active and inactive X chromosomes during mitosis
In mammals, chromosome-wide regulatory mechanisms ensure a balance of X-linked gene dosage between males (XY) and females (XX). In female cells, expression of genes from one of the two X-chromosomes is curtailed, with selective accumulation of Xist-RNA, Xist-associated proteins, specific histone mod...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-23 | PXD054014 | Pride
Proteomics Mitotic Mouse Chromosomes 
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