Sort   by:  
 Page size 
ProteomicsProximity labeling and identification of the proteins that interact with Siglec-14 on THP-1 cells
Proteins that interact with Siglec-14 were identified by proximity labeling, followed by streptavidin affinity purification and proteomic analysis. MaxQuant software was used for the quantitative analysis of the proteins identified.
ORGANISM(S): Homo sapiens (Human) 
2018-11-04 | PXD009748 | Pride
Siglec-14 Proximity labeling Cis-ligand Thp-1 
ProteomicsIdentification of Siglec ligands in human B cell
Siglecs are a family of receptor-type glycan recognition proteins (lectins) involved in self - nonself discrimination by the immune system. Identification of Siglec ligand(s) is necessary to understand how Siglec-ligand interaction translates to biological outcomes, but is challenging because the in...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2017-09-29 | PXD006359 | Pride
Proteomics Siglec Sialic acid 
TranscriptomicsGene expression profiles of Siglec-14/THP-1 and Siglec-5/THP cell lines, with or without NTHi stimulation
Acquisition of a new strain of non-typeable Haemophilus influenzae (NTHi) is often associated with exacerbation of chronic obstructive pulmonary disease (COPD). We have previously reported that COPD patients who are homozygous null for SIGLEC14 gene is less susceptible to COPD exacerbation than thos...
ORGANISM(S): Homo sapiens 
2014-08-04 | E-GEOD-47929 | biostudies-arrayexpress
ProteomicsIdentification of Siglec-7-ligand candidates on JVM-3 human B cell line by proximity labeling
Siglec-7 is a member of Siglec family of glycan recognition proteins involved in the regulation of natural killer (NK) cell activities. We found Siglec-7 ligand is highly expressed on JVM-3, a B cell chronic lymphocytic leukemia (B-CLL) cell line. In this experiment, we attempted at identifying th...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD024690 | Pride
Human Lc-msms Siglec-7 Ligand B cell Sialic acid 
Sort   by:  
 Page size