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TranscriptomicsInflammatory mediators alter astrocyte genomic profiles and G-protein receptor evoked calcium signaling
Inflammation features in diverse central nervous system disorders such as stroke, trauma, neurodegeneration, infection and autoimmunity. To better understand how inflammatory mediators may alter astrocyte functions, we examined the effects of transforming growth factor-β1 (TGF-β1), lipopolysacchar...
ORGANISM(S): Mus musculus 
2012-10-18 | E-GEOD-36089 | biostudies-arrayexpress
ProteomicsProteome of human and mouse astrocytes and astrocyte-conditioned medium
Proteome of human and mouse astrocytes and astrocyte-conditioned medium
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-02-05 | PXD060495 |
ProteomicsDevelopmental alcohol exposure leads to a persistent change on astrocyte secretome
Glial cells are central players in the pathogenesis of neurodevelopmental disorders like Fetal Alcohol Spectrum Disorder (FASD). Ethanol can modulate glial differentiation and astrocyte function imposing dramatic changes to the developing brain. Since ethanol can affect a vast number of intracellula...
ORGANISM(S): Mustela putorius furo (European domestic ferret) (Mustela furo) 
2016-02-15 | PXD002787 | Pride
Astrocytes Secretome Ethanol Fasd 
ModelsMartínJiménez2017 - Genome-scale reconstruction of the human astrocyte metabolic network
MartínJiménez2017 - Genome-scale reconstruction of the human astrocyte metabolic network This model is described in the article: Genome-Scale Reconstruction of the Human Astrocyte Metabolic Network. Martín-Jiménez CA, Salazar-Barreto D, Barreto GE, González J. Front Aging Neur...
2017-05-18 | MODEL1608180000 | BioModels
ProteomicsProteomics of TurboID-induced biotinylated proteins from astrocyte and astrocyte endeet after acute peripheral inflammation
The brain vasculature is tightly regulated to control the exchange of substances between the periphery and the brain parenchyma at an interface called the blood-brain barrier (BBB). Astrocytes are glial cells that wrap the brain vasculature with a specialised structure called the endfoot, which is a...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-11 | PXD056232 | Pride
Mouse Brain Dia Ip Endfoot Isolation Astrocyte 
TranscriptomicsEffects of Hsp72 on astrocyte activation following stroke in the mouse
Astrogliosis is a hallmark of the response to brain ischemia, comprised of changes in gene expression and morphology. Hsp72 protects from cerebral ischemia, and although several mechanisms of protection have been investigated, effects on astrocyte activation are unknown. To identify potential mecha...
ORGANISM(S): Mus musculus 
2013-01-11 | E-GEOD-28731 | biostudies-arrayexpress
ProteomicsMouse brain perivascular astrocyte endfoot proteome
Proteome analysis of isolated mouse brain blood vessels and perivascular astrocyte endfeet (PV-AEF) using DIA.
ORGANISM(S): Mus Musculus (mouse) 
2023-11-04 | PXD037949 | JPOST Repository
MetabolomicsTime-Restricted Feeding Orchestrates Astrocytic Metabolic Reprogramming via the Wnt Pathway to Alleviate Sevoflurane-Induced Neural Injury

Perioperative neurocognitive disorders (PND) pose a significant challenge for aging surgical patients, with sevoflurane anesthesia being an identified risk factor. Time-restricted feeding (TRF), a dietary regimen, shows promise in mitigating age-related cognitive decline, but its efficacy and mec...

2026-02-17 | MTBLS13891 | MetaboLights
GenomicsSequentially Acting SOX Proteins Orchestrate Astrocyte and Oligodendrocyte Specific Gene Expression
Sequentially Acting SOX Proteins Orchestrate Astrocyte and Oligodendrocyte Specific Gene Expression
PRJNA483960 | ENA
ProteomicsAstrocyte proteome from the rat substantia nigra. Study in animal model of fluorocitrate-induced astrocyte dysfunction and microglia activation.
Dysfunction of astrocytic support for prolonged time can be harmful for nervous system. Inflammation and glia activation are among hallmarks of most neurodegenerative diseases. Therefore, astrocytes are considered as druggable targets for disease modifying strategies. Partial lesion of dopaminergic ...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-02-11 | PXD067265 | Pride
Proteomics Lc-ms Fluorocitrate Astrocyte Substantia nigra 
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