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ProteomicsNotch Signaling Enhances Bone Regeneration in the Zebrafish Mandible
Loss or damage to the mandible due to trauma, treatment of oral malignancies, and other diseases is currently treated using bone grafting techniques that suffer from numerous shortcomings and contraindications. Zebrafish naturally heal large injuries to their mandibular bone, and thus offer an oppor...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2022-03-07 | PXD027280 | Pride
Proteomics Chondrocytes Notch signaling Mass spectrometry Q exactive hf Bone Fasp Mandible Zebrafish 
ProteomicsMethylation of Ciliary Dynein Motors Involves the Essential Cytosolic Assembly Factor DNAAF3/PF22
Axonemal dynein motors drive ciliary motility and can consist of up to twenty distinct components with a combined mass of ~2 MDa. In mammals, failure of dyneins to assemble within the axonemal superstructure leads to primary ciliary dyskinesia. Syndromic phenotypes include infertility, rhinitis, sev...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-02-12 | PXD045935 | Pride
Methylation Ptm Dynein Cilia 
ProteomicsCellular and extracellular composition of meningeal trabeculae
The meninges are a tripartite system of membranous tissue comprised of pial, arachnoid and dural layers that cover both the brain and spinal cord. Between the arachnoid and pial layers is the subarachnoid space filled with cerebrospinal fluid (CSF). Though the meninges have long been thought to prov...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-01 | PXD039294 | Pride
Brain Shotgun proteomics Trabeculae Multiple sclerosis Extracellular Meninges Spinal cord 
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