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ProteomicsCharacterization of Ksg1 protein kinase-dependent phosphoproteome in the fission yeast S. pombe
Ksg1 is an essential protein kinase of the fission yeast S. pombe that belongs to the AGC kinase family and is homologous to the mammalian PDPK1 kinase. Previous studies have shown that Ksg1 functions in the nutrient-sensing TOR signaling pathway and is involved in the phosphorylation and activation...
ORGANISM(S): Schizosaccharomyces pombe 
2024-11-02 | PXD054277 | Pride
Ksg1 Kinase S.pombe Phosphoproteome 
ProteomicsGPATCH11 ortholog Sap34 regulates pre-mRNA splicing by interacting with early spliceosomal complexes in Schizosaccharomyces pombe
Pre-mRNA splicing is an essential step in gene expression regulation. It is mediated by the spliceosome, a large ribonucleoprotein complex that undergoes dynamic structural and compositional rearrangements during each splicing cycle. Although the mechanisms of splicing and the roles of main spliceos...
ORGANISM(S): Schizosaccharomyces pombe 927 
2026-04-21 | PXD077306 | Pride
G-patch protein  sap34  spac6f6.19  splicing factor  pre-mrna splicing  fission yeast 
ProteomicsLabel-Free Phosphoproteomics Profiling of Fission Yeast Schizosaccharomyces pombe
The phosphorylation of proteins modulates various functions of proteins and plays an important role in regulation of cell signaling. In the recent years, the label-free quantitative (LFQ) phos-phoproteomics has become the powerful tool to analyze the phosphorylation of proteins within the complex sa...
ORGANISM(S): Schizosaccharomyces pombe 927 
2021-02-12 | PXD023818 | Pride
Pgc Schizosaccharomyces pombe Sax Lfq phosphoproteomics 
ProteomicsMechanisms Regulating the Function of Spliceosome-Associated Factor Nrl1 of the Fission Yeast Schizosaccharomyces pombe
Pre-mRNA splicing is a key process in the regulation of gene expression as reflected by its disruption in various diseases. Previously, we have demonstrated that the spliceosome-associated factor Nrl1 of the fission yeast S. pombe, except of its role in suppression of accumulation of genome-threaten...
ORGANISM(S): Schizosaccharomyces pombe 927 
2021-07-12 | PXD026669 | Pride
Nrl1  pre-mrna splicing  protein-protein interactions  phosphorylation  cka1  fission yeast 
ProteomicsHighly flexible metabolism of the marine euglenozoan protist Diplonema papillatum
Diplonema papillatum represents a group of highly diverse and abundant marine protists with still unknown lifestyle and ecological functions. Based on alterations of the transcriptomic, proteomic and metabolomic profiles obtained from cells grown under different conditions we designed a metabolic ma...
ORGANISM(S): Diplonema papillatum 
2021-11-15 | PXD025411 | Pride
Metabolism Euglenozoans Diplonema papillatum Hypoxia Mitochondrion 
ProteomicsReduction of ribosomal expansion segments in yeast species of the Magnusiomyces/Saprochaete clade
Ribosomes are ribonucleoprotein complexes highly conserved across all domains of life. The size differences of ribosomal RNAs (rRNAs) can be mainly attributed to variable regions termed expansion segments (ESs) protruding out from the ribosomal surface. Although the ESs were found to be involved in ...
ORGANISM(S): Dipodascus albidus Magnusiomyces capitatus 
2024-08-01 | PXD043413 | Pride
Magnusiomyces Yeast Ribosome Expansion segments Ribosomal rna 
ProteomicsYeast mitochondrial succinylome: Implications for mitochondrial DNA maintenance
Together with other post-translational modifications, acylation of proteins is a powerful means of regulation of their activity. Some acylation types occur nonenzymatically and are driven by an increase in the concentration of acyl group donors. Lysine succinylation has a profound effect on the corr...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-10-26 | PXD023604 | Pride
Succinylation Ptm Mitochondria Yeast 
ProteomicsTranscriptional landscape of Candida parapsilosis cells assimilating hydroxyaromatic substrates
The pathogenic yeast Candida parapsilosis can utilize a wide range of hydroxyaromatic substrates as sole carbon sources through the 3-oxoadipate pathway (3-OAP) and the gentisate pathway (GP). It was previously established that the genes coding for the components of these pathways are arranged in tw...
ORGANISM(S): Candida parapsilosis 
2022-02-01 | PXD024608 | Pride
Hydroxybenzene Peroxisome Yeast Biochemical pathway evolution Catabolism Hydroxybenzoate Metabolic gene cluster Transcription activator 
ProteomicsQuantitative Proteomics and Phosphoproteomics Profiling of Meiotic Cell Divisions in the Fission Yeast Schizosaccharomyces pombe
In eukaryotes, chromosomal DNA is equally distributed to daughter cells during mitosis, whereas the number of chromosomes is halved during meiosis. Despite considerable progress in understanding the molecular mechanisms that regulate mitosis, there is currently a lack of complete understanding of th...
ORGANISM(S): Schizosaccharomyces pombe 927 
2024-10-09 | PXD053920 | Pride
Phosphoproteome Schizosaccharomyces pombe Meiosis Pat1 protein kinase 
UnknownVasopressor use after noncardiac surgery: an international observational study.
Not available
S-EPMC12799376 | biostudies-literature
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