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TranscriptomicsTranscription profiling of Medicago roots from MtTi2i vs control after infection with Aphanomyces euteiches
Comparsion of root transcriptome profiles after Aphanomyces euteiches infections between control and MtTi2i-lines
ORGANISM(S): Medicago truncatula 
2006-03-03 | E-MEXP-572 | biostudies-arrayexpress
UnknownSilencing of the sulfur rich α-gliadin storage protein family in wheat grains (Triticum aestivum L.) causes no unintended side-effects on other metabolites.
Not available
S-EPMC3775129 | biostudies-literature
ProteomicsModular Vinyl-Phosphonamidates for Cysteine Directed Protein Targeting
Covalent inhibitors and chemical probes targeting ligandable cysteine residues have emerged as powerful tools in drug discovery and proteomics. In this study, we introduce vinyl-phosphonamidates (VPAs) as a novel class of latent cysteine electrophiles and assess their reactivity, selectivity, and po...
ORGANISM(S): Homo sapiens (Human) 
2026-03-09 | PXD064073 | Pride
Chemoproteomics Covalent inhibitors 
TranscriptomicsExpression data from Burkholderia cenocepacia J2315 hfq and hfq2 mutants
Hfq proteins are RNA chaperones that play a critical role in post-transcription regulation of gene expression. Bacteria of the Burkholderia cepacia complex harbor two distinct and functional Hfq proteins, the Hfq and Hfq2. We have previously performed the functional analysis of Hfq and Hfq2 in the p...
ORGANISM(S): Burkholderia cenocepacia 
2014-01-01 | E-GEOD-47344 | biostudies-arrayexpress
ProteomicsA High-salt diet induces immune-independent re-differentiation of melanoma, metabolic shut down and cell-cycle arrest
A high salt diet (HSD) is known to reduce cancer growth in some models, due to accumulation of sodium in the skin, which enhanced local anti-tumor immunity. Here we show that a HSD inhibits melanoma growth in both skin and lung, independent from sodium accumulation and from immune cells. Melanoma ce...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-02 | PXD057160 | Pride
Melanogenesis Tmtpro Mouse Lc-ms3 Melanoma High salt diet 
TranscriptomicsDeep sequencing of the murine olfactory receptor neuron transcriptome
The recent development of next-generation sequencing (NGS) techniques encouraged us to assess the transcriptome of the murine OE. We analyzed RNA from OEs of female and male adult mice and from fluorescence-activated cell sorting (FACS)-sorted olfactory receptor neurons (ORNs) obtained from transgen...
ORGANISM(S): Mus musculus 
2015-01-21 | E-GEOD-53793 | biostudies-arrayexpress
UnknownSystematic association mapping identifies NELL1 as a novel IBD disease gene.
Not available
S-EPMC1933598 | biostudies-literature
TranscriptomicsEndometrial methylome of patients without endometriosis
Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes and the menstrual cycle phase-dependent epigenetic signature should be ...
ORGANISM(S): Homo sapiens 
2016-02-15 | E-GEOD-73949 | biostudies-arrayexpress
TranscriptomicsEndometrial methylome of patients with endometriosis
Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes and the menstrual cycle phase-dependent epigenetic signature should be ...
ORGANISM(S): Homo sapiens 
2016-02-15 | E-GEOD-73948 | biostudies-arrayexpress
ProteomicsTargeted approach to determine the impact of cancer-associated protease variants
Several mechanisms of cancer progression, from tumour onset to metastasis, critically involve proteolytic activity. Studying the role of proteases in cancer, it is important to consider single nucleotide variants (SNVs) affecting the active site of proteases, that might impact cleavage specificity, ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD048501 | Pride
Snvs Meprin β Proteases Cancer Migration Spheroids Cancer-associated variants Cleavage specificity N-terminomics Organotypic brain slices 
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