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Comparsion of root transcriptome profiles after Aphanomyces euteiches infections between control and MtTi2i-lines
ORGANISM(S): Medicago truncatula 
Hfq proteins are RNA chaperones that play a critical role in post-transcription regulation of gene expression. Bacteria of the Burkholderia cepacia complex harbor two distinct and functional Hfq proteins, the Hfq and Hfq2. We have previously performed the functional analysis of Hfq and Hfq2 in the p...
ORGANISM(S): Burkholderia cenocepacia 
Covalent inhibitors and chemical probes targeting ligandable cysteine residues have emerged as powerful tools in drug discovery and proteomics. In this study, we introduce vinyl-phosphonamidates (VPAs) as a novel class of latent cysteine electrophiles and assess their reactivity, selectivity, and po...
ORGANISM(S): Homo sapiens (Human) 
2026-03-09 | PXD064073 | Pride
A high salt diet (HSD) is known to reduce cancer growth in some models, due to accumulation of sodium in the skin, which enhanced local anti-tumor immunity. Here we show that a HSD inhibits melanoma growth in both skin and lung, independent from sodium accumulation and from immune cells. Melanoma ce...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-02 | PXD057160 | Pride
The recent development of next-generation sequencing (NGS) techniques encouraged us to assess the transcriptome of the murine OE. We analyzed RNA from OEs of female and male adult mice and from fluorescence-activated cell sorting (FACS)-sorted olfactory receptor neurons (ORNs) obtained from transgen...
ORGANISM(S): Mus musculus 
Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes and the menstrual cycle phase-dependent epigenetic signature should be ...
ORGANISM(S): Homo sapiens 
Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes and the menstrual cycle phase-dependent epigenetic signature should be ...
ORGANISM(S): Homo sapiens 
Acute kidney injury is strongly associated with mortality in COVID-19 patients. However, host cell changes underlying infection of kidney cells with SARS-CoV-2 remain unknown and prevent understanding of the mechanisms leading to renal pathology. Here, we carried out extensive, dual-level proteomic ...
ORGANISM(S): Homo sapiens (Human) 
2022-01-30 | PXD024398 | Pride
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