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ProteomicsTarget Landscape of Clinical Kinase Inhibitors
Here, we provide a comprehensive overview of the selectivity profiles of 242 kinase inhibitors currently in clinical trials. We screened available inhibitors against human protein kinases by using the Kinobead technology resulting in a drug matrix identifying the druggable kinome and related protein...
ORGANISM(S): Homo sapiens (Human) 
2017-12-01 | PXD005336 | Pride
Target Mass spectrometry Chemical proteomics Kinase inhibitors Clinical kinase inhibitors Selectivity Lc-ms/ms 
UnknownNitrogen-Functionalized Hydrothermal Carbon Materials by Using Urotropine as the Nitrogen Precursor.
Not available
S-EPMC6120519 | biostudies-literature
ProteomicsA High-salt diet induces immune-independent re-differentiation of melanoma, metabolic shut down and cell-cycle arrest
A high salt diet (HSD) is known to reduce cancer growth in some models, due to accumulation of sodium in the skin, which enhanced local anti-tumor immunity. Here we show that a HSD inhibits melanoma growth in both skin and lung, independent from sodium accumulation and from immune cells. Melanoma ce...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-02 | PXD057160 | Pride
Melanogenesis Tmtpro Mouse Lc-ms3 Melanoma High salt diet 
UnknownEpigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis.
Not available
S-EPMC8492348 | biostudies-literature
UnknownRetinoic acid drives intestine-specific adaptation of effector ILC2s originating from distant sites.
Not available
S-EPMC10541314 | biostudies-literature
UnknownInfluenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair.
Not available
S-EPMC4913929 | biostudies-literature
UnknownPost-neoadjuvant cellular dissociation grading based on tumour budding and cell nest size is associated with therapy response and survival in oesophageal squamous cell carcinoma.
Not available
S-EPMC6964693 | biostudies-literature
ProteomicsProteome analysis of Beas-2B cells with S. pneumoniae D39
Proteome analysis of Beas-2B cells with S. pneumoniae D39 after 9 h and 16 h of infection
ORGANISM(S): Homo sapiens (Human) 
2023-07-04 | PXD039059 | Pride
Streptococcus pneumoniae Proteomics Infection Beas-2b 
Unknown(+)-[18F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand-results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer's disease and healthy controls.
Not available
S-EPMC8036219 | biostudies-literature
UnknownNAD+ metabolism is a key modulator of bacterial respiratory epithelial infections.
Not available
S-EPMC10545792 | biostudies-literature
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