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ProteomicsProteomics analysis on cottonseed meal protein isolate extract-ed using improved gossypol removal method
Cottonseed meal (CSM) contains a high amount of underutilised proteins due to the presence of gossypol, a toxic compound unsuitable for human consumption. We designed a protein extract process to generate CSM protein isolate (CSMPI) with ultra-low gossypol content to unlock their potential. This pro...
ORGANISM(S): Gossypium hirsutum 
2022-10-13 | PXD029330 | Pride
Cottonseed meal  gossypol  proteomics  acidified organic solvent-based gossypol removal  alka-line-based protein solubilisation  allergen 
ProteomicsDevelopment and characterization of vorinostat resistant cutaneous T cell lymphoma cells
Vorinostat is the very first approved inhibitor of histone deacetylase, widely used in many countries for the treatment of primary/ persistent cutaneous T cell lymphoma (CTCL). However, problems associated with intrinsic and acquired resistance to vorinostat present a significant challenge to therap...
ORGANISM(S): Homo sapiens (Human) 
2026-09-08 | PXD026689 | Pride
Erk Vorinostat resistance Silac proteomics Rnaseq analysis 
ProteomicsA comprehensive CHO SWATH-MS spectral library for accurate quantitative profiling of 10k proteins
A comprehensive Chinese hamster ovary (CHO)-cell specific spectral library, containing extensive information of high-quality spectral ions covering more than 10k CHO cell proteins, was constructed to provide confident and reproducible protein identification and quantification in data-independent SWA...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2020-07-20 | PXD016047 | Pride
Tripletof 6600 Swath-ms Chinese hamster ovary cells Lc-ms/ms 
ProteomicsProteomic Profiling of Barley Spent Grains
Proteomic profiling was performed on barley spent grain. Spent grain from malted barley and from raw barley supplemented with exogenous enzymes were profiled.
ORGANISM(S): Hordeum vulgare (Barley) 
2018-03-23 | PXD008090 | Pride
Barley Spent grain 
ProteomicsSWATH-MS insights on butyric acid effect on mAbs production and redox homeostasis in CHO cells.
Sodium butyrate (NaBu) is well-known for its capacity to hinder cellular growth and act as a histone deacetylase inhibitor. It is commonly employed in the cultivation of recombinant Chinese hamster ovary (CHO) cell cultures to boost the production of specific proteins, such as antibodies. In this in...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2025-05-06 | PXD048575 | Pride
Lc-msms Redox Swath-ms Cho cells Mabs production Butyric acid 
ProteomicsCAPTURE2.0 pull-down of SINE-MIR associated proteins in mouse embryonic stem cells
In mouse embryonic stem cells, the regulators of transposable elements are not well known. Here, we studied the proteins regulating mammalian-wide interspersed repeat (MIR), a short-interspersed nuclear elements (SINE) family using the CAPTURE2.0 system. We generated cell lines expressing biotinylat...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-01 | PXD062330 | Pride
Mouse Transposable elements Tmt Embryonic stem cells Lc-ms/ms 
ProteomicsTemporal Insights into Molecular and cellular responses during rAAV production in HEK293T cells
To understand the dynamic role of HEK293T cells at different cellular states post-transfection we have performed a comprehensive comparative proteome profiling of the host cell system post-transfection at 24, 48, and 72 hpt. For this study, we developed an in-house label-free HEK293T-AAV spectral li...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD046574 | Pride
Hek293t Spectral library Swath-ms 
ProteomicsProteomic profiling of New Zealand endemic Porphyra/Pyropia (karengo) seaweeds: A predictive framework for functional food applications
Porphyra/Pyropia seaweeds are promising sources for functional foods development, offering a rich macro- and micronutrient profiles. In New Zealand (NZ), endemic Porphyra/Pyropia species (karengo), exhibit considerable variability driven by geography, seasonality, and climate, which may influence th...
ORGANISM(S): Bangiaceae 
2026-02-09 | PXD069102 | Pride
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