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Protein secretion into extracellular space is an important virulence mechanism both among Gram negative and Gram-positive bacteria. Prevotella intermedia, an important species associated with periodontitis, is known to be resistant to several antibiotics. Since P. intermedia is a part of normal oral...
ORGANISM(S): Prevotella intermedia ATCC 25611 = DSM 20706 
2022-05-19 | PXD029419 | Pride
Protein phosphorylation has a major role in controlling the life-cycle and infection stages of bacteria. Proteome-wide occurrence of S/T/Y phosphorylation has been reported for many prokaryotic systems. Previously, we reported the phosphoproteome of Pseudomonas aeruginosa and Pseudomonas putida. In ...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2022-03-02 | PXD003645 | Pride
Staphylococcus aureus and Staphylococcus epidermidis, two Gram-positive bacteria commonly found in the human skin microbiota, form biofilms that contribute to skin dysbiosis and play a key role in conditions like acne and atopic dermatitis. The Calcitonin Gene-Related Peptide (CGRP) is a human pepti...
ORGANISM(S): Staphylococcus aureus 
2026-03-09 | PXD062742 | Pride
Lon protease is a global regulator in bacteria, affecting biofilm formation, antibiotic resistance, toxin-antitoxin complexes and proteolysis of damaged proteins. This study uses bottom-up proteomics to identify Klebsiella pneumoniae proteins with altered secretion patterns in the absence of lon and...
ORGANISM(S): Klebsiella pneumoniae 
2024-11-01 | PXD057415 | Pride
Bacterial exopolysaccharide (EPS) formation is crucial for biofilm formation, protection against environmental factors or as storage compounds. EPSs produced by lactic acid bacteria (LAB) are appropriate for applications in food fermentation or the pharmaceutical industry, yet the dynam-ics of forma...
ORGANISM(S): Levilactobacillus brevis 
2022-03-21 | PXD031809 | Pride
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