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ProteomicsDeep Dive in the Proteome of Human Cerebrospinal Fluid: A Valuable Data Resource for Biomarker Discovery and Missing Protein Identification
Cerebrospinal fluid (CSF) is a body fluid of choice for biomarker studies of brain disorders but remains relatively under-studied compared to other biological fluids such as plasma, partly due to the more invasive means of its sample collection. The present study establishes an in-depth CSF proteome...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-12 | MSV000083965 | MassIVE
ProteomicsProteomic Profiling of the Human Tissue and Biological Fluid Proteome
Here, we performed label-free liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) to profile the normal human proteome. In total, we analyzed 117 samples from 46 histologically normal tissues and organs at autopsy. Our high-resolution MS approach allowed for the quantification of 10...
ORGANISM(S): Homo sapiens (Human) 
2020-10-29 | PXD020192 | Pride
Biological fluid proteome Tissue proteome Mass spectrometry Brain regions Lc-ms/ms 
ProteomicsProteomics of cerebrospinal fluid microvesicles
Comprehensive proteomic dataset of cerebrospinal fluid (CSF) microvesicles. The aim of this study is to deeply characterize the protein content of microvesicles (MVs) isolated from human cerebrospinal fluid. MVs were isolated from Two CSF pools and their proteome was studied with high sensitivity ma...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-23 | MSV000080277 | MassIVE
ProteomicsProteome Profiling in Cerebrospinal Fluid Reveals Novel Biomarkers of Alzheimer’s Disease
Neurodegenerative diseases are a growing burden and there is an urgent need for better biomarkers for diagnosis, prognosis and treatment efficacy. Structural and functional brain alterations are reflected in the protein composition of cerebrospinal fluid (CSF). Alzheimer’s disease (AD) patients ha...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-01-06 | MSV000088649 | MassIVE
ProteomicsPhosphoproteome Analysis of Cerebrospinal Fluid Extracellular Vesicles in Primary Central Nervous System Lymphoma
Primary central nervous system lymphoma(PCNSL) is a rare extra-nodal non-Hodgkin’s lymphoma and accounts for 3%-4% of central nervous system tumors. Recent studies have highlighted the importance of cerebrospinal fluid derived extracellular vesicles in PCNSL. Extracellular vesicles(EVs) are nanoscal...
ORGANISM(S): Homo Sapiens (human) 
2023-07-12 | PXD040744 | JPOST Repository
ProteomicsA normative study of the synovial fluid proteome from healthy porcine knee joints
Synovial fluid in an articulating joint contains proteins derived from blood transudates, and proteins that are produced by cells within joint tissues, such as synovium, cartilage, ligament, and meniscus. The proteome composition of healthy synovial fluid is not fully understood. Also not fully deli...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2014-09-09 | PXD000935 | Pride
Proteomics Method optimization Human Ptm Synovial fluid Plasma Transcriptomics Synovium Porcine Origin 
ProteomicsThe Amniotic Fluid Proteome Changes Across Gestation in Humans and Rhesus Macaques
Amniotic fluid is a complex biological medium that offers mechanical protection and nutrition to the fetus, and also plays a key role in normal fetal growth, organogenesis, and potentially fetal programming. Amniotic fluid is also critically involved in longitudinally shaping the in utero milieu dur...
ORGANISM(S): Homo sapiens (Human) Macaca mulatta (Rhesus macaque) 
2023-10-24 | PXD043519 | Pride
Rhesus macaque Isobaric labeling Pregnancy Amniotic fluid Quantitative proteomics 
OtherProteomic analysis of cerebrospinal fluid extracellular vesicles: A comprehensive dataset.
Data from ProteomeXchange, PXD ID: PXD000608. File: QE1_120417_OPL0006_16_CSFexosomes_SP_DC_G3.mzml. Published as part of J Proteomics. 2014 Apr 24 . From the Abstract: {{i}} Extracellular vesicles (EVs) are present in human cerebrospinal fluid (CSF), yet little is known about their protein composi...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310000045 | GPMDB
Resource Reanalysis 
ProteomicsProteome of paediatric burn wound fluid collected via negative pressure wound therapy
Negative pressure wound therapy (NPWT) has been used to promote wound healing in a variety of settings, including as an adjunct to silver-impregnated dressings in the acute management of paediatric burns. Fluid aspirated by the NPWT system represents a potentially insightful research matrix for unde...
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD023168 | Pride
Exudate Proteomics Swath Paediatric Effluent Npwt Oedema fluid Burn Blister fluid Lc-ms/ms 
ProteomicsProteome of paediatric burn wound fluid collected via negative pressure wound therapy
Negative pressure wound therapy (NPWT) has been used to promote wound healing in a variety of settings, including as an adjunct to silver-impregnated dressings in the acute management of paediatric burns. Fluid aspirated by the NPWT system represents a potentially insightful research matrix for unde...
ORGANISM(S): Homo sapiens (Human) 
2022-08-15 | PXD023161 | Pride
Exudate Proteomics Swath Paediatric Effluent Npwt Oedema fluid Burn Blister fluid Lc-ms/ms 
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