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UnknownAPMAP interacts with lysyl oxidase-like proteins, and disruption of <i>Apmap</i> leads to beneficial visceral adipose tissue expansion.
Not available
S-EPMC5566180 | biostudies-literature
ProteomicsComparative proteomics of paired human vocal fold and oral mucosa tissue
This dataset brief is about the descriptive proteomic comparison of human oral mucosa and vocal fold tissues by high-resolution mass spectrometry (CID-MS/MS). The vast majority of voice disorders is associated with changes of the unique but delicate tissue of the human vocal folds, wheras the abili...
ORGANISM(S): Homo sapiens (Human) 
2021-12-30 | PXD025519 | Pride
Oral mucosa Comparative proteomics Human tissue Vocal folds 
ProteomicsOlfactory cleft proteome does not reflect olfactory performance in patients with idiopathic and postinfectious olfactory disorder: A pilot study.
The pathophysiology of post-infectious and idiopathic olfactory loss is still poorly delineated. Since proteins are key players in olfaction and technical advances including LC-MS/MS mass spectrometry give us the opportunity for detailed analysis of the nasal mucus proteome we aimed to undertake a c...
ORGANISM(S): Homo sapiens (Human) 
2018-12-10 | PXD009172 | Pride
Human Olfactory cleft Idiopathic and postinfectious olfactory disorder Lc-ms/ms 
ProteomicsMCM proteins are up-regulated in placentas of women with reduced insulin sensitivity
In the first trimester of pregnancy the human placenta grows rapidly, making it sensitive to changes in the intrauterine environment. To test whether exposure to an environment in utero often associated with obesity modifies placental proteome and function, we performed untargeted proteomics (LC-MS/...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD056380 | Pride
Obesity Placenta Mcm-complex Early pregnancy Insulin Oxygen Placenta-growth Dna-damage repair Insulin sensitivity Trophoblast 
UnknownTsr4 and Nap1, two novel members of the ribosomal protein chaperOME.
Not available
S-EPMC6648895 | biostudies-literature
ProteomicsComparative Proteomics of PairedVocal Fold and Oral Mucosa Fibroblasts
Injuries of the vocal folds frequently heal with scar formation, which can have lifelong detrimental impact on voice quality. Current treatments to prevent or resolve scars of the vocal fold mucosa are highly unsatisfactory. In contrast, the adjacent oral mucosa is mostly resistant to scarring. Thes...
ORGANISM(S): Ovis aries 
2017-01-23 | PXD005106 | Pride
Lamina propria Oral mucosa Wound healing Fibrosis Laryngology Scar Vocal folds Fibroblasts 
ProteomicsOptimized data analysis avoiding trypsin artefacts
Most bottom-up proteomics experiments share two features: The use of trypsin to digest proteins for mass spectrometry and the statistic driven matching of the measured peptide fragment spectra against protein database derived in silico generated spectra. While this extremely powerful approach in com...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-04-15 | PXD002726 | Pride
Autolysis protected trypsin Data base search 
UnknownEffect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs.
Not available
S-EPMC6102642 | biostudies-literature
ProteomicsRbp95 binds 25S rRNA helix H95 and cooperates with the Npa1 complex during early pre-60S particle maturation
Eukaryotic ribosome synthesis involves more than 200 assembly factors, which promote ribosomal RNA (rRNA) processing, modification and folding, and assembly of ribosomal proteins. The formation and maturation of the earliest pre-60S particles requires structural remodeling by the Npa1 complex, but i...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-13 | PXD030106 | Pride
Ribosome assembly factor Yeast S. cerevisiae Tandem-affinity purification (tap) Npa1 Pre-60s particles Rbp95 
ProteomicsInvestigation of hepatic stellate cell proteomics during activa-tion with fetal bovine serum
Hepatic stellate cells (HSCs) are the major driving factor in liver fibrosis. Upon liver inflammation caused by alcohol abuse and/or a fatty liver, HSCs transform from a quiescent- into a proliferating, fibrotic phenotype. We study this transformation termed “activation”, using state of the art TIMS...
ORGANISM(S): Homo sapiens (Human) 
2022-02-14 | PXD029121 | Pride
Human Proteomics Activation Fibrosis Liver Hepatic stellate cells 
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