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TranscriptomicsDifferential gene expression profiling of MIHA cells transfected with C-terminal truncated HBx mutants
To compare the differentially expressed transcriptomes between MIHA cells transfected with empty vector control or different C-terminal truncated HBx mutants (14 or 35 amino acid carboxyl-terminal truncation - i.e. d14 and d35) mRNA profiles of MIHA cells stably overexpressing empty vector control o...
ORGANISM(S): Homo sapiens 
2016-08-02 | E-GEOD-71993 | biostudies-arrayexpress
ProteomicsOne-step Isolation of Protein C-terminal Peptides from Protease-digested Proteins by Metal Oxide-based Ligand Exchange Chromatography
We have developed a one-step method to isolate protein C-terminal peptides from V8-digested proteins by metal oxide-based ligand-exchange (MOLEX) chromatography. V8 protease cleaves the C-terminal side of Asp and Glu, and the resulting digested peptide has two carboxy groups at the C-terminus, where...
ORGANISM(S): Homo Sapiens (human) 
2021-12-28 | PXD027960 | JPOST Repository
GenomicsProtein C-Terminal Variations Impact Proteostasis
Protein C-Terminal Variations Impact Proteostasis
PRJNA1269061 | ENA
OtherLysargiNase mirrors trypsin for protein C-terminal and methylation-site identification.
Data from ProteomeXchange: PXD ID: PXD001114. Experiment: LysargiNase, silac, file: LR_Ulilysin_PMA_A1_121126.mzml. Published as part of . From the Abstract: {{i}} To improve proteome coverage and protein C-terminal identification, we characterized the Methanosarcina acetivorans thermophilic protei...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32310005457 | GPMDB
Resource Reanalysis 
GenomicsChIP-seq of C-terminal FLAG-tagged WhiA
ChIP-seq of C-terminal FLAG-tagged WhiA
PRJEB104001 | ENA
ProteomicsInvestigating N-terminal shedding of GPR125 in GPR125 overexpressing HEK293T cells using N- and C-terminal enrichment and different cleavage strategies
The study was conducted to elucidate potential cleavage sites of GPR125 which are known to undergo N-terminal shedding through autoproteolysis in a region different to other GRPs. To do these different enzymatic strategies as well as enrichment of both N-terminal and C-terminal peptides, was conduct...
ORGANISM(S): Homo sapiens (Human) 
2026-08-31 | PXD083139 | Pride
Gpr125 Scx C-terminal Lysate Hek293t Enrichment Lc-msms Adra3 N-terminal Medium 
ProteomicsPhotoredox-catalyzed decarboxylative C-terminal differentiation for bulk and single molecule proteomics
Methods for the selective labeling of functional groups on peptides are being developed and used in the workflow of both current and emerging proteomics technologies, such as single-molecule fluorosequencing. Photoredox methods in discriminative targeting of the terminal carboxylic acid from the int...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Homo Sapiens (ncbitaxon:9606) Saccharomyces Cerevisiae (ncbitaxon:4932) 
2021-06-01 | MSV000087551 | MassIVE
GenomicsC-terminal Occludin Peptide Suppresses Airway Inflammation via Barrier Restoration
C-terminal Occludin Peptide Suppresses Airway Inflammation via Barrier Restoration
PRJNA1373223 | ENA
ProteomicsC-terminal amides mark proteins for degradation via SCF/FBXO31 – CTAP discovery
FBXO31 is a substrate adapter for the SCF-type ubiquitin ligase complex SCF/FBXO31 which ubiquitylates C-terminal amide-bearing proteins (CTAPs), thereby triggering their proteasomal degradation in human cells. CTAPs can arise from internal protein cleavage events during which the N-terminal fragme...
ORGANISM(S): Homo sapiens (Human) 
2024-11-05 | PXD055814 | Pride
C-terminal amide Oxidative stress Ubiquitin ligase Fbxo31 
ProteomicsExopeptidase assisted N- and C-terminal proteome sequencing
Due to mechanisms such as alternative translation starts or proteolytic processing, in-vivo proteoforms do not necessarily correspond to those encoded in the genome. Therefore, knowledge of protein termini is an indispensable prerequisite to understand protein function. Sequencing of protein N- and ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-10-15 | PXD015612 | Pride
Protein sequencing Proteomics Terminomics 
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